Patient Data
The healthcare provider (HCP) has given the client a prescription for captopril.
Choose the most likely options for the information missing from the statements by selecting from the lists of options provided.
Captopril is a(n)
The Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"D"}
Captopril is an angiotensin converting enzyme inhibitor that works by vasodilation.
Choice A: Angiotensin Converting Enzyme Inhibitor
Reason:
Captopril is classified as an angiotensin converting enzyme (ACE) inhibitor. ACE inhibitors work by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this conversion, ACE inhibitors reduce the levels of angiotensin II, leading to vasodilation, decreased blood pressure, and reduced workload on the heart. This mechanism is particularly beneficial in managing hypertension and heart failure. Additionally, ACE inhibitors like captopril help in reducing the progression of diabetic nephropathy by decreasing glomerular pressure.
Choice B: Aldosterone Agonist
Reason:
Aldosterone agonists are drugs that mimic the action of aldosterone, a hormone that increases sodium and water reabsorption in the kidneys, leading to increased blood volume and blood pressure. This is the opposite of what captopril does. Captopril, as an ACE inhibitor, actually reduces aldosterone secretion, leading to decreased sodium and water retention, which helps lower blood pressure. Therefore, captopril cannot be classified as an aldosterone agonist.
Choice C: Angiotensin II Receptor Blocker
Reason:
Angiotensin II receptor blockers (ARBs) work by blocking the action of angiotensin II at its receptor sites, preventing vasoconstriction and aldosterone secretion. While ARBs and ACE inhibitors both target the renin-angiotensin-aldosterone system (RAAS), they do so at different points. Captopril is an ACE inhibitor, not an ARB. ARBs include drugs like losartan and valsartan, which are used when patients cannot tolerate ACE inhibitors due to side effects like coug.
Choice D: Lowering the Heart Rate
Reason:
Lowering the heart rate is not the primary mechanism of action for captopril. This effect is more commonly associated with beta-blockers, which reduce heart rate and myocardial contractility to lower blood pressure and reduce cardiac workload. Captopril, on the other hand, primarily works through vasodilation by inhibiting the formation of angiotensin II. While it may have some indirect effects on heart rate by reducing blood pressure, this is not its main mechanism.
Choice E: Reducing Inflammation
Reason:
Reducing inflammation is not a primary action of captopril. Anti-inflammatory effects are typically associated with nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids. While there is some evidence that ACE inhibitors may have minor anti-inflammatory effects due to their impact on the RAAS, this is not their primary function. Captopril is mainly used for its vasodilatory effects to manage hypertension and heart failure.
Choice F: Diuresis
Reason:
Diuresis, or increased urine production, is not the primary mechanism of action for captopril. Diuretics, such as furosemide or hydrochlorothiazide, are specifically used to promote diuresis by acting on different parts of the renal tubules to increase the excretion of sodium and water. While captopril can lead to mild diuresis by reducing aldosterone levels, this is not its main therapeutic action.
Choice G: Vasodilation
Reason:
Vasodilation is the correct mechanism of action for captopril. By inhibiting the conversion of angiotensin I to angiotensin II, captopril reduces vasoconstriction and promotes vasodilation. This leads to a decrease in blood pressure and an overall reduction in the workload on the heart. Vasodilation is a key therapeutic effect of ACE inhibitors, making them effective in treating conditions like hypertension and heart failure.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A Reason:
Avoiding taking the medication on an empty stomach is important to reduce gastrointestinal upset. Lithium can cause stomach irritation, and taking it with food can help mitigate this side effect. However, while this is good advice, it is not the most critical instruction to emphasize.
Choice B Reason:
Reporting fluctuations in weight to the healthcare provider is essential because significant weight changes can indicate potential side effects or complications from lithium therapy. Weight gain or loss can be a sign of thyroid dysfunction or other metabolic issues. While important, it is not the primary instruction to emphasize.
Choice C Reason:
Maintaining a fluid intake of 1500 to 2000 mL per day is crucial for clients taking lithium. Lithium levels in the blood can be affected by fluid balance, and dehydration can lead to lithium toxicity. Ensuring adequate hydration helps maintain stable lithium levels and reduces the risk of toxicity. This is the most critical instruction to emphasize to ensure the client’s safety and effective management of their condition.
Choice D Reason:
Keeping medication fliers for frequent review and reference is helpful for understanding the medication and its potential side effects. However, it is not the most critical instruction. The primary focus should be on maintaining proper hydration to prevent lithium toxicity.
Correct Answer is ["A","B","C","E"]
Explanation
Choice A reason:
Lisinopril is an ACE inhibitor that is commonly prescribed for once-daily dosing. It is effective in managing hypertension and heart failure with a single daily dose, making it convenient for patients who may have difficulty remembering multiple doses12.
Choice B reason:
Quinapril can also be administered once daily. It is used to treat hypertension and heart failure, and its long half-life allows for effective blood pressure control with a single daily dose
Choice C reason:
Ramipril is another ACE inhibitor that can be given once daily. It is used for hypertension, heart failure, and to reduce the risk of cardiovascular events. Its pharmacokinetics support once-daily dosing, which helps improve patient adherence.
Choice D reason:
Captopril is typically not given once daily due to its shorter half-life. It usually requires multiple doses throughout the day to maintain effective blood pressure control.
Choice E reason:
Trandolapril is an ACE inhibitor that can be administered once daily. It is used for hypertension and heart failure, and its long duration of action supports once-daily dosing.
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