A nurse is collecting a medication history from a client who is scheduled to have a cardiac catheterization. Which of the following medications taken by the client interacts with contrast material and places the client at risk for acute kidney injury?
Metformin
Carvedilol
Nitroglycerin
Atorvastatin
None
None
The Correct Answer is A
Choice A: Metformin
Reason: Metformin is known to interact with contrast material, particularly iodinated contrast media, and can increase the risk of acute kidney injury (AKI). This interaction can lead to a condition known as contrast-induced nephropathy (CIN) or contrast-induced acute kidney injury (CI-AKI). Metformin is primarily excreted by the kidneys, and impaired renal function can lead to its accumulation, increasing the risk of lactic acidosis, a rare but serious complication. Therefore, it is generally recommended to withhold metformin before and after the administration of contrast media until renal function is confirmed to be normal.

Choice B: Carvedilol
Reason: Carvedilol is a beta-blocker used to treat high blood pressure and heart failure. It does not have a known interaction with contrast media that would increase the risk of acute kidney injury. Carvedilol primarily affects the cardiovascular system and does not significantly impact renal function or interact with contrast agents.
Choice C: Nitroglycerin
Reason: Nitroglycerin is used to treat angina and other heart conditions by dilating blood vessels. It does not interact with contrast media in a way that would increase the risk of acute kidney injury. Nitroglycerin’s primary effects are on the cardiovascular system, and it does not have nephrotoxic properties.
Choice D: Atorvastatin
Reason: Atorvastatin is a statin used to lower cholesterol levels. While it can have effects on liver enzymes and muscle tissue, it does not interact with contrast media to increase the risk of acute kidney injury. Atorvastatin is metabolized by the liver and does not significantly impact renal function.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason:
Strict monitoring of hourly intake and output is important for managing fluid balance and detecting potential complications such as dehydration or fluid overload1. However, it is not the highest priority in the acute phase of bacterial meningitis. The primary concern is to monitor for signs of increased intracranial pressure (ICP) and neurological deterioration.
Choice B reason:
Managing pain through drug and non-drug methods is essential for patient comfort and overall well-being. Pain management can help reduce stress and improve the patient’s ability to rest and recover. However, it is not the highest priority compared to monitoring neurological status, which can provide early indications of complications such as increased ICP or seizures.
Choice C reason:
Assessing neurological status at least every 2 to 4 hours is the highest priority for a client with bacterial meningitis. This frequent assessment helps detect early signs of neurological deterioration, increased ICP, and other complications. Early detection and intervention are crucial in preventing severe outcomes and improving the patient’s prognosis.

Choice D reason:
Decreasing environmental stimuli is important to reduce stress and prevent exacerbation of symptoms such as headache and photophobia. While this intervention is beneficial, it is not as critical as frequent neurological assessments in the acute management of bacterial meningitis.
Correct Answer is ["A","B","D"]
Explanation
Choice A reason: Pink frothy sputum is a classic sign of pulmonary edema, which can occur as a result of oxygen toxicity. When the alveoli in the lungs fill with fluid, it can lead to this type of sputum. This is a critical indicator that the client is experiencing severe respiratory distress and requires immediate medical attention.
Choice B reason: Substernal discomfort or chest pain is another symptom of oxygen toxicity. This discomfort arises due to the irritation and inflammation of the lung tissues caused by high levels of oxygen. It is essential to monitor and address this symptom promptly to prevent further complications.
Choice C reason: Nail clubbing is typically associated with chronic hypoxia and long-term lung diseases, but it is not an acute indicator of oxygen toxicity. Therefore, it is not relevant in this context.
Choice D reason: Restlessness is a common early sign of hypoxia and can also indicate oxygen toxicity. When the brain does not receive adequate oxygen, it can lead to symptoms such as restlessness, confusion, and agitation. This symptom should be taken seriously and addressed immediately.
Choice E reason: Cyanosis at the nail beds indicates a lack of oxygen in the blood, but it is not specific to oxygen toxicity. It can occur in various conditions where there is inadequate oxygenation, such as chronic obstructive pulmonary disease (COPD) or heart failure.
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