The Correct Answer is {"dropdown-group-1":"A"}
Clubbing is a medical condition characterized by bulbous enlargement of the distal portion of a digit (usually a finger, but sometimes a toe) due to soft tissue proliferation and increased bone deposition. The affected digit takes on a rounded or "club-like" appearance, and the angle between the nail and nail bed (known as the Lovibond angle) increases to greater than 180 degrees.
Clubbing is commonly associated with a variety of medical conditions that interfere with oxygenation of the blood, including lung diseases such as chronic obstructive pulmonary disease (COPD), interstitial lung disease, and bronchiectasis; heart diseases such as congenital heart defects and cyanotic heart disease; and gastrointestinal diseases such as inflammatory bowel disease and cirrhosis.
The exact mechanism underlying clubbing is not fully understood, but it is thought to involve a combination of vascular, inflammatory, and neurogenic factors. Hypoxia (low oxygen levels) is believed to play a central role in the development
of clubbing, leading to the release of growth factors and cytokines that promote soft tissue and bone proliferation.
Clubbing is typically diagnosed based on physical examination findings, including the Lovibond angle and the presence of nail bed fluctuation (when the nail bed feels spongy or compressible). It is important to identify and treat any underlying medical conditions that may be contributing to clubbing, as these can have significant implications for the patient's health and quality of life.
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Correct Answer is D
Explanation
Chronic bronchitis is a type of chronic obstructive pulmonary disease (COPD) that is characterized by inflammation and narrowing of the bronchial tubes, which can lead to symptoms such as cough, shortness of breath, and wheezing. The primary cause of chronic bronchitis is smoking, and the most effective way to halt its progression is by quitting smoking.
Smoking cessation is the cornerstone of treatment for chronic bronchitis, as continued smoking can worsen inflammation in the airways and accelerate the progression of the disease. In addition to smoking cessation, other treatments may include bronchodilators (such as albuterol) to help open the airways and improve breathing, postural chest drainage techniques to help clear mucus from the lungs, and antibiotics to treat bacterial infections.
While these treatments can help manage symptoms and prevent complications, they are not as effective as smoking cessation in halting the progression of chronic bronchitis. Therefore, it is important for individuals with chronic bronchitis to quit smoking as soon as possible to slow the disease process and improve their overall health.
Correct Answer is C
Explanation
Modifiable risk factors for coronary artery disease (CAD) are those that can be changed or controlled to reduce the risk of developing CAD. These include high blood pressure, high cholesterol levels, smoking, physical inactivity, unhealthy diet, and obesity. High HDL (high-density lipoprotein) is actually a desirable factor, as it is known as the "good cholesterol" and helps to remove excess cholesterol from the body. Orthostatic hypotension, or a drop in blood pressure upon standing, is not considered a modifiable risk factor for CAD.
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