Which immunoglobulin may contribute to the pathophysiology of asthma
IgA
IgE
C. IgG
IgM
The Correct Answer is B
IgE is the immunoglobulin associated with allergic reactions and is often elevated in patients with asthma. When a person with asthma is exposed to an allergen, their IgE levels increase, leading to the release of inflammatory chemicals such as histamine, which can cause bronchoconstriction and other symptoms of asthma.
IgA: This is an immunoglobulin that plays a role in the immune system's defense against infections. It is mainly found in the mucous membranes of the respiratory and gastrointestinal tracts.
IgG: This is the most abundant immunoglobulin in the bloodstream and plays a role in providing immunity against bacterial and viral infections. It can also cross the placenta and provide passive immunity to a developing fetus.
IgM: This is the first immunoglobulin produced in response to an infection and plays a role in the body's defense against bacterial and viral infections. It is found primarily in the bloodstream.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
The correct answer is B. Systolic pressure less than 120 mmHg and diastolic pressure less than 80 mmHg is considered normal blood pressure in adults according to current guidelines. A systolic pressure between 140-150 mmHg (option A) would be classified as stage 1 hypertension, while a systolic pressure greater than 140 mmHg and diastolic pressure of 100 mmHg (option D) would be classified as stage 2 hypertension. A systolic pressure less than 100 mmHg regardless of diastolic pressure (option C) would be considered low blood pressure.
Correct Answer is B
Explanation
Calcium channel blockers (CCBs) are a class of medications that block the influx of calcium ions into cardiac and smooth muscle cells, leading to relaxation of these muscles and dilation of blood vessels.
In the heart, CCBs primarily affect the L-type calcium channels in the cardiac myocytes, which are responsible for the influx of calcium ions during the plateau phase of the cardiac action potential. By blocking these channels, CCBs decrease the amount of calcium that enters the cardiac myocytes, which in turn reduces the strength of cardiac contractions (i.e. contractility). 
This reduction in contractility can be beneficial in certain conditions where the heart is working too hard or experiencing insufficient blood flow, such as in hypertension, angina, or some forms of arrhythmia. By reducing the workload of the heart, CCBs can help to lower blood pressure, decrease oxygen demand, and improve blood flow to the heart.
While CCBs can also have effects on the rate and rhythm of cardiac contractions, these effects are generally less pronounced than the reduction in contractility. Some CCBs, such as verapamil and diltiazem, can slow the heart rate by blocking the L-type calcium channels in the sinoatrial (SA) and atrioventricular (AV) nodes, while others, such as nifedipine, have little effect on heart rate.
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