Circulation is vital because it:

Pathogens are disease-causing agents. They can be bacteria, viruses, fungi, protists, or parasitic worms.
They can infect other organisms and cause various diseases.
Choice A is wrong because phagocytic leukocytes are a type of white blood cell that can engulf and destroy pathogens.
They are part of the immune system and help fight infections.
Choice B is wrong because antibodies are proteins that can bind to specific antigens on the surface of pathogens and mark them for destruction by other immune cells.
They are also part of the immune system and help fight infections.
Choice D is wrong because agents that alter DNA base sequences are not necessarily pathogens.
They can be mutagens, such as chemicals or radiation, that can cause changes in the DNA of cells.
Some mutagens can also be carcinogens, which can cause cancer.

It explains that the primary immune response produces antibodies within five to ten days of exposure to antigens, while the secondary immune response produces antibodies within a day or two of subsequent exposure to the same antigen.
This is because the primary immune response involves the activation and differentiation of naive B cells into plasma cells and memory cells, while the secondary immune response involves the rapid activation of memory cells into plasma cells.
Choice A is wrong because the primary and secondary immune responses can occur in both children and adults.
Choice B is wrong because the primary immune response is slower than the secondary immune response in producing antibodies.
Choice D is wrong because both primary and secondary immune responses are important for the body’s ability to protect itself from pathogens.
The primary immune response generates immunological memory, while the secondary immune response provides a faster and stronger response to repeated infections.