The normal pacemaker of the heart is the:

This is because it is an example of a positive feedback loop, which amplifies the change and moves the system away from its normal state.
A negative feedback loop is a mechanism that reverses a deviation from the set point and maintains homeostasis.
Choice A is wrong because increasing heart rate and force of contraction when blood pressure falls is a negative feedback loop that restores blood pressure to normal.
Choice B is wrong because secreting insulin after a meal to return blood sugar concentration toward normal is a negative feedback loop that regulates glucose levels.
Choice D is wrong because shivering when body temperature falls below normal is a negative feedback loop that increases heat production and raises body temperature.
Normal ranges for blood pressure are 90/60 mmHg to 120/80 mmHg, for blood glucose, are 70 mg/dL to 140 mg/dL, and for body temperature are 36.5°C to 37.5°C or 97.7°F to 99.5°F.

The sinoatrial (SA) node is the natural pacemaker of the heart.
It generates electrical impulses that cause the heart’s chambers to contract, setting the heart rate.
The SA node typically generates 60–100 heartbeats per minute when a person is at rest.
Choice A is wrong because Purkinje fibers are part of the electrical conduction system of the heart that carries impulses to the ventricles.
They are not the primary source of impulses.
Choice B is wrong because the AV bundle (also called bundle of His) is another part of the electrical conduction system of the heart that connects the atria and the ventricles.
It is not the natural pacemaker of the heart.
Choice D is wrong because an atrioventricular node is a relay station between the atria and the ventricles that delays the electrical impulses from the SA node.
It can act as a backup pacemaker if the SA node fails, but it is not the normal pacemaker of the heart.