Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?

This answer is correct because BSA is the most accurate method for calculating the child's dose from the adult dose¹². BSA takes into account the child's weight and height, and reflects the physiological function and organ growth of the child beter than weight alone¹. BSA can be calculated using a nomogram or a formula based on the child's weight and height¹. The child's dose can then be calculated by multiplying the adult dose by the ratio of the child's BSA to the average adult BSA (1.73 m2)¹. For example:

Child dose by BSA = (mg/day) = Adult Dose in mg/day x BSA in m2 / 1.73

OR

Child dose by BSA = (mg/day) = Adult Dose in mg/m2 x BSA in m2

The other options are not correct because they are not accurate methods for calculating the child's dose from the adult dose. Actual body weight and ideal body weight may not account for individual variations in pharmacokinetics, pharmacodynamics, or clinical response. Actual body height is not a reliable indicator of drug dosage, as it does not reflect the body mass or organ function of the child.

Subcutaneous injection is the usual route for giving insulin because it allows the medication to be absorbed slowly and steadily into the bloodstream. Subcutaneous injection involves inserting a needle into the faty layer of tissue under the skin, usually in the abdomen, upper arm, thigh, or butock.

Intramuscular injection is not the usual route for giving insulin because it may cause rapid and unpredictable absorption of the medication, which can lead to hypoglycemia or hyperglycemia. Intramuscular injection involves inserting a needle into the muscle tissue, usually in the deltoid, vastus lateralis, or ventrogluteal area.

Intraosseous injection is not the usual route for giving insulin because it is reserved for emergency situations when intravenous access is not available. Intraosseous injection involves inserting a needle into the bone marrow, usually in the tibia or humerus.

Intradermal injection is not the usual route for giving insulin because it is mainly used for diagnostic tests, such as tuberculin skin test or allergy test. Intradermal injection involves inserting a needle into the dermis, which is the layer of skin just below the epidermis, usually in the forearm or upper back.