Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?
4.6 mL
5.9 mL
66.9 mL
6.49 mL
12.4 mL
The Correct Answer is D
To find the amount of solution to draw for one dose, you need to calculate the following:
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)
First, use the formula for BSA to find the client's body surface area in square meters:
BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:
BSA (m²) = √(148 cm x 55 kg / 3600)
Simplify and solve for the BSA:
BSA (m²) = 1.41 m²
Next, use the formula for dose to find the amount of allopurinol in milligrams:
Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)
Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:
Dose (mg) = 1.41 m² x 115 mg/m²
Simplify and solve for the dose:
Dose (mg) = 162.15 mg
Then, use the formula for volume to find the amount of solution in milliliters:
Volume (mL) = Dose (mg) / Concentration (mg/mL)
Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:
Volume (mL) = 162.15 mg / 25 mg/mL
Simplify and solve for the volume:
Volume (mL) = 6.486 mL
Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.
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Related Questions
Correct Answer is B
Explanation
To find the milliliters per dose, you need to use the formula for dosage calculation:
Volume (mL) = Dose ordered (mg) / Concentration (mg/mL) x Volume available (mL)
Since the dose ordered is 0.5 grams, the concentration is 125 mg/5 mL, and the volume available is 5 mL, plug in these values into the formula:
Volume (mL) = 0.5 grams / 125 mg/5 mL x 5 mL
However, before you can simplify and solve for the volume, you need to convert the dose from grams to milligrams by multiplying by 1000:
Volume (mL) = 500 mg / 125 mg/5 mL x 5 m
Simplify and solve for the volume:
Volume (mL) = 20 mL
Therefore, the nurse should administer **20 mL** of Amoxil per dose to the patient.
Correct Answer is A
Explanation
To find the number of capsules of amoxicillin required for 5 days, you need to calculate the following:
- The total dose of amoxicillin in milligrams (mg) for 5 days using the formula: Total dose (mg) = Prescribed dose (mg) x Frequency (times/day) x Duration (days)
- The number of capsules of amoxicillin using the formula: Number of capsules = Total dose (mg) / Strength per capsule (mg)
First, use the formula for total dose to find the amount of amoxicillin in milligrams for 5 days:
Total dose (mg) = Prescribed dose (mg) x Frequency (times/day) x Duration (days)
Since the prescribed dose is 250 mg, the frequency is 3 times per day, and the duration is 5 days, plug in these values into the formula:
Total dose (mg) = 250 mg x 3 times/day x 5 days
Simplify and solve for the total dose:
Total dose (mg) = 3750 mg
Next, use the formula for number of capsules to find how many capsules of amoxicillin are needed:
Number of capsules = Total dose (mg) / Strength per capsule (mg)
Since the total dose is 3750 mg and the strength per capsule is 250 mg, plug in these values into the formula:
Number of capsules = 3750 mg / 250 mg
Simplify and solve for the number of capsules:
Number of capsules = 15
Therefore, the client needs **15 capsules** of amoxicillin for 5 days.
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