Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?
4.6 mL
5.9 mL
66.9 mL
6.49 mL
12.4 mL
The Correct Answer is D
To find the amount of solution to draw for one dose, you need to calculate the following:
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)
First, use the formula for BSA to find the client's body surface area in square meters:
BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:
BSA (m²) = √(148 cm x 55 kg / 3600)
Simplify and solve for the BSA:
BSA (m²) = 1.41 m²
Next, use the formula for dose to find the amount of allopurinol in milligrams:
Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)
Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:
Dose (mg) = 1.41 m² x 115 mg/m²
Simplify and solve for the dose:
Dose (mg) = 162.15 mg
Then, use the formula for volume to find the amount of solution in milliliters:
Volume (mL) = Dose (mg) / Concentration (mg/mL)
Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:
Volume (mL) = 162.15 mg / 25 mg/mL
Simplify and solve for the volume:
Volume (mL) = 6.486 mL
Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
This action should be taken by the nurse before administering the medication because the use of a trailing zero after a decimal point (5.0 mg) is a common cause of medication errors and should be avoided. A trailing zero may be misread or misinterpreted as a larger dose (50 mg) or omited altogether, resulting in a 10-fold overdose or underdose, respectively. For example, when prescriptions have been writen for "Coumadin 1.0 mg," patients have received 10 mg in error. Therefore, the nurse should clarify the intended dose with the healthcare provider and use the correct notation (5 mg) without a trailing zero.
The other options are not appropriate actions because:
a) Discussing the use of PO (by mouth) with the healthcare provider is not necessary, as PO is a standard route of administration for Haldol (haloperidol) and does not pose a risk of confusion or error.
b) Discussing the use of tid (three times a day) with the healthcare provider is not necessary, as tid is a standard frequency of administration for Haldol and does not pose a risk of confusion or error.
c) Discussing the use of Haldol with the healthcare provider is not relevant to the question, as Haldol is the prescribed medication for the patient who is agitated and does not need to be changed or questioned by the nurse.
Correct Answer is D
Explanation
The nurse should administer 4 mL to this patient.
This answer is correct because it is based on a simple ratio and proportion calculation. The nurse can set up a proportion as follows:
2 mg / 1 mL = 8 mg / x mL
Cross-multiplying and solving for x gives:
x = 4 mL
Therefore, the nurse should administer 4 mL of ondansetron to deliver 8 mg of the medication to the patient.
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