Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?
4.6 mL
5.9 mL
66.9 mL
6.49 mL
12.4 mL
The Correct Answer is D
To find the amount of solution to draw for one dose, you need to calculate the following:
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)
First, use the formula for BSA to find the client's body surface area in square meters:
BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:
BSA (m²) = √(148 cm x 55 kg / 3600)
Simplify and solve for the BSA:
BSA (m²) = 1.41 m²
Next, use the formula for dose to find the amount of allopurinol in milligrams:
Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)
Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:
Dose (mg) = 1.41 m² x 115 mg/m²
Simplify and solve for the dose:
Dose (mg) = 162.15 mg
Then, use the formula for volume to find the amount of solution in milliliters:
Volume (mL) = Dose (mg) / Concentration (mg/mL)
Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:
Volume (mL) = 162.15 mg / 25 mg/mL
Simplify and solve for the volume:
Volume (mL) = 6.486 mL
Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.
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Related Questions
Correct Answer is A
Explanation
To calculate the infusion rate, we need to convert the patient's weight from kilograms to milligrams.
Patient's weight: 65 kg
Dose required: 200 mcg/kg/min
First, let's calculate the total dose required for the patient per minute: Dose required = 200 mcg/kg/min * 65 kg
= 13,000 mcg/min
Next, we need to convert the dose from micrograms to milligrams:
13,000 mcg/min = 13 mg/min
Now, let's determine the infusion rate. We have 2,500 mg of esmolol in 250 mL of fluid. Therefore, the concentration of esmolol in the fluid is:
Concentration = 2,500 mg / 250 mL
= 10 mg/mL
To find the infusion rate, we divide the dose required by the concentration: Infusion rate = 13 mg/min / 10 mg/mL
= 1.3 mL/mi
Since the options are in mL/hr, we need to convert the rate from mL/min to mL/hr:
1.3 mL/min * 60 min/hr = 78 mL/hr
Therefore, the correct answer is:
a. 78 mL/hr
Correct Answer is C
Explanation
The instruction that should be given to this client for the effective management of hypertension is to take
**five tablets** of bisoprolol per day, each containing 100 mg.
This is because the new order of 500 mg of bisoprolol per day is twice as much as the current dose of 250 mg of bisoprolol per day (two and a half tablets of 100 mg each). Therefore, the client needs to double the number of tablets they take per day from two and a half to five.
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