Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?
4.6 mL
5.9 mL
66.9 mL
6.49 mL
12.4 mL
The Correct Answer is D
To find the amount of solution to draw for one dose, you need to calculate the following:
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)
First, use the formula for BSA to find the client's body surface area in square meters:
BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:
BSA (m²) = √(148 cm x 55 kg / 3600)
Simplify and solve for the BSA:
BSA (m²) = 1.41 m²
Next, use the formula for dose to find the amount of allopurinol in milligrams:
Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)
Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:
Dose (mg) = 1.41 m² x 115 mg/m²
Simplify and solve for the dose:
Dose (mg) = 162.15 mg
Then, use the formula for volume to find the amount of solution in milliliters:
Volume (mL) = Dose (mg) / Concentration (mg/mL)
Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:
Volume (mL) = 162.15 mg / 25 mg/mL
Simplify and solve for the volume:
Volume (mL) = 6.486 mL
Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
First, we need to convert the patient's weight from pounds to kilograms using the conversion factor 1 kg =
2.2 lb:
154 lb / 2.2 lb/kg = 70 kg
Next, we need to calculate the dose of nitroprusside in mcg/min using the formula Dose = Weight × Dosage:
Dose = 70 kg × 3 mcg/kg/min = 210 mcg/min
Then, we need to convert the dose of nitroprusside from mcg/min to mg/hr using the conversion factor 1 mg = 1000 mcg:
210 mcg/min × 1 mg/1000 mcg × 60 min/hr = 12.6 mg/hr
Finally, we need to calculate the rate of nitroprusside in mL/hr using the formula Rate = Dose/Concentration:
Rate = 12.6 mg/hr / 100 mg/mL = 0.126 mL/hr
To round to the nearest hundredth, we get 0.13 mL/hr, which is approximately equal to 1.26 mL/hr.
Therefore, the nurse should program the IV pump to deliver nitroprusside at a rate of 1.26 mL/hr.
Correct Answer is B
Explanation
Subcutaneous injection is the usual route for giving insulin because it allows the medication to be absorbed slowly and steadily into the bloodstream. Subcutaneous injection involves inserting a needle into the faty layer of tissue under the skin, usually in the abdomen, upper arm, thigh, or butock.
Intramuscular injection is not the usual route for giving insulin because it may cause rapid and unpredictable absorption of the medication, which can lead to hypoglycemia or hyperglycemia. Intramuscular injection involves inserting a needle into the muscle tissue, usually in the deltoid, vastus lateralis, or ventrogluteal area.
Intraosseous injection is not the usual route for giving insulin because it is reserved for emergency situations when intravenous access is not available. Intraosseous injection involves inserting a needle into the bone marrow, usually in the tibia or humerus.
Intradermal injection is not the usual route for giving insulin because it is mainly used for diagnostic tests, such as tuberculin skin test or allergy test. Intradermal injection involves inserting a needle into the dermis, which is the layer of skin just below the epidermis, usually in the forearm or upper back.
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