Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?
4.6 mL
5.9 mL
66.9 mL
6.49 mL
12.4 mL
The Correct Answer is D
To find the amount of solution to draw for one dose, you need to calculate the following:
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)
First, use the formula for BSA to find the client's body surface area in square meters:
BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:
BSA (m²) = √(148 cm x 55 kg / 3600)
Simplify and solve for the BSA:
BSA (m²) = 1.41 m²
Next, use the formula for dose to find the amount of allopurinol in milligrams:
Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)
Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:
Dose (mg) = 1.41 m² x 115 mg/m²
Simplify and solve for the dose:
Dose (mg) = 162.15 mg
Then, use the formula for volume to find the amount of solution in milliliters:
Volume (mL) = Dose (mg) / Concentration (mg/mL)
Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:
Volume (mL) = 162.15 mg / 25 mg/mL
Simplify and solve for the volume:
Volume (mL) = 6.486 mL
Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
To find how much medication to administer, you need to calculate the following:
- The volume of diphenhydramine in milliliters
- The infusion time in minutes
First, divide the dose of diphenhydramine by the concentration to get the volume in milliliters:
25 mg / 50 mg/mL = 0.5 mL diphenhydramine should be diluted in 10 to 20 mL of normal saline and infused over at least 2 minutes.
Therefore, the nurse should administer **0.5 mL** of diphenhydramine diluted in 10 to 20 mL of normal saline over **at least 2 minutes**.
The nurse should administer this medication **as soon as possible** after receiving the order and the medication from the pharmacy, as STAT means immediately or urgently. The nurse should also monitor the client for signs of improvement or adverse reactions.
Correct Answer is D
Explanation
To find the answer, we need to convert the units of the medication order and the infusion rate to the same units. We can use the following conversions:
1 mcg = 0.001 mg 1 kg = 1000 g 1 min = 60 s 1 h = 3600 s
The medication order is 140 mcg/kg/min, which means the patient needs 140 mcg of medication per kilogram of body weight per minute. The patient weighs 60 kg, so we multiply 140 mcg by 60 kg to get the total amount of medication per minute:
140 mcg/kg/min x 60 kg = 8400 mcg/min
We then convert this to milligrams by dividing by 1000:
8400 mcg/min / 1000 = 8.4 mg/min
The infusion rate is 10 mL/h, which means the patient receives 10 mL of fluid per hour. We convert this to minutes by dividing by 60:
10 mL/h / 60 = 0.167 mL/min
We can now find the concentration of the medication in the fluid by dividing the amount of medication per minute by the amount of fluid per minute:
8.4 mg/min / 0.167 mL/min = 50.3 mg/mL
This means that for every milliliter of fluid, there are 50.3 milligrams of medication. To find how many milligrams of medication are in one hour, we multiply the concentration by the infusion rate:
50.3 mg/mL x 10 mL/h = 503 mg/h
This is the total amount of medication that the patient receives in one hour. To find how many milligrams are in one dose, we divide this by the number of doses per hour, which is one:
503 mg/h / 1 dose/h = 503 mg/dose
This is the final answer, but we need to round it to the nearest tenth, as per the instructions: 503 mg/dose ≈ 67.2 mg/dose
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