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Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?

A.

4.6 mL

B.

5.9 mL

C.

66.9 mL

D.

6.49 mL

E.

12.4 mL

Answer and Explanation

The Correct Answer is D

To find the amount of solution to draw for one dose, you need to calculate the following:
 
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)


First, use the formula for BSA to find the client's body surface area in square meters:


BSA (m²) = √(Height (cm) x Weight (kg) / 3600)


Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:


BSA (m²) = √(148 cm x 55 kg / 3600)


Simplify and solve for the BSA:


BSA (m²) = 1.41 m²


Next, use the formula for dose to find the amount of allopurinol in milligrams:


Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)


Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:


Dose (mg) = 1.41 m² x 115 mg/m²


Simplify and solve for the dose:


Dose (mg) = 162.15 mg


Then, use the formula for volume to find the amount of solution in milliliters:
 

Volume (mL) = Dose (mg) / Concentration (mg/mL)


Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:


Volume (mL) = 162.15 mg / 25 mg/mL


Simplify and solve for the volume:


Volume (mL) = 6.486 mL


Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.


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Related Questions

Correct Answer is C

Explanation

To find the hours to finish the infusion, you need to calculate the following:

- The volume of saline solution in milliliters
- The time in hours using the formula: Time (h) = Total volume (mL) / Infusion rate (mL/h)


First, convert the volume of saline solution from liters to milliliters by multiplying by 1000:

1.5 L x 1000 = 1500 mL


Next, use the formula for time to find how many hours it will take to infuse the saline solution at the current rate:


Time (h) = Total volume (mL) / Infusion rate (mL/h)


Since the total volume is 1500 mL and the infusion rate is 75 mL/h, plug in these values into the formula:


Time (h) = 1500 mL / 75 mL/h


Simplify and solve for the time:


Time (h) = 20 h


Therefore, it will take **20 hours** to finish the infusion at the current rate.

Correct Answer is B

Explanation

To find the rate in mL/hr, you need to use the formula for infusion rate:


Infusion rate (mL/h) = Total volume (mL) / Time (h)


Since the total volume is 500 mL and the time is 2 hours, plug in these values into the formula:


Infusion rate (mL/h) = 500 mL / 2 h


Simplify and solve for the infusion rate:


Infusion rate (mL/h) = 250 mL/h


Therefore, the nurse should set the IV pump to deliver **250 mL/h** to infuse LR 500 mL over 2 hours.

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