Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?
4.6 mL
5.9 mL
66.9 mL
6.49 mL
12.4 mL
The Correct Answer is D
To find the amount of solution to draw for one dose, you need to calculate the following:
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)
First, use the formula for BSA to find the client's body surface area in square meters:
BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:
BSA (m²) = √(148 cm x 55 kg / 3600)
Simplify and solve for the BSA:
BSA (m²) = 1.41 m²
Next, use the formula for dose to find the amount of allopurinol in milligrams:
Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)
Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:
Dose (mg) = 1.41 m² x 115 mg/m²
Simplify and solve for the dose:
Dose (mg) = 162.15 mg
Then, use the formula for volume to find the amount of solution in milliliters:
Volume (mL) = Dose (mg) / Concentration (mg/mL)
Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:
Volume (mL) = 162.15 mg / 25 mg/mL
Simplify and solve for the volume:
Volume (mL) = 6.486 mL
Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Step 1 is Convert pounds to kilograms 110 lb ÷ 2.2 = 50 kg
Step 2 is Calculate dose in micrograms per minute 50 kg × 200 micrograms = 10,000 micrograms/min
Step 3 is Convert micrograms to milligrams 10,000 micrograms ÷ 1000 = 10 mg/min
Step 4 is Convert mg/min to mg/hr 10 mg × 60 = 600 mg/hr
Step 5 is Determine concentration of esmolol in mg/mL 2.5 grams × 1000 = 2500 mg 2500 mg ÷ 250 mL = 10 mg/mL
Step 6 is Calculate infusion rate in mL/hr 600 mg/hr ÷ 10 mg/mL = 60 mL/hr
Correct Answer is B
Explanation
The dose of the medicine per day is 1.8 mcg.
This answer is correct because it is based on a simple multiplication calculation. The nurse should follow these steps to calculate the dose of the medicine per day:
1) Divide 24 hours by the frequency of the dose to get the number of doses per day, as follows:
24 / 4 = 6
Therefore, the client will receive 6 doses of the medicine per day.
2) Multiply the number of doses per day by the amount of each dose to get the total dose per day, as follows:
6 x 0.3 mcg = 1.8 mcg
Therefore, the dose of the medicine per day is 1.8 mcg.
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