Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?
4.6 mL
5.9 mL
66.9 mL
6.49 mL
12.4 mL
The Correct Answer is D
To find the amount of solution to draw for one dose, you need to calculate the following:
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)
First, use the formula for BSA to find the client's body surface area in square meters:
BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:
BSA (m²) = √(148 cm x 55 kg / 3600)
Simplify and solve for the BSA:
BSA (m²) = 1.41 m²
Next, use the formula for dose to find the amount of allopurinol in milligrams:
Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)
Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:
Dose (mg) = 1.41 m² x 115 mg/m²
Simplify and solve for the dose:
Dose (mg) = 162.15 mg
Then, use the formula for volume to find the amount of solution in milliliters:
Volume (mL) = Dose (mg) / Concentration (mg/mL)
Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:
Volume (mL) = 162.15 mg / 25 mg/mL
Simplify and solve for the volume:
Volume (mL) = 6.486 mL
Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
To answer this question, the nurse needs to perform the following steps:
1) Convert the patient's weight from pounds and ounces to kilograms, using the conversion factor of 1 pound = 0.45359237 kilograms¹². To do this, first convert the ounces to a fraction of a pound by dividing by 16, then add this fraction to the pounds, and then multiply by the conversion factor. For example:
7 lb, 11.2 oz = 7 + (11.2 / 16) lb
= 7.7 lb
= 7.7 × 0.45359237 kg
= 3.492 kg
2) Calculate the dose of Garamycin in milligrams, using the prescribed dose of 4 mg/kg and the patient's weight in kilograms. To do this, simply multiply the dose per kilogram by the weight in kilograms. For example:
4 mg/kg × 3.492 kg = 13.968 mg
3) Calculate the volume of Garamycin in milliliters, using the reconstituted dosage of 20 mg/10 mL and the dose in milligrams. To do this, use a proportion to find the unknown volume that corresponds to the known dose. For example:
20 mg / 10 mL = 13.968 mg / x mL Cross-multiply and solve for x: 20x = 139.68
x = 6.984 mL
x =7 mL
Correct Answer is C
Explanation
To calculate the rate (in mL/hr) at which the IV pump should be programmed to deliver the dose of esmolol, we can use the following formula:
Rate (mL/hr) = (Dose × Patient weight × 60) / (Concentration × Time)
Given:
Dose = 2.5 grams Patient weight = 110 lb Concentration = 250 mL
Time = 1 hour (since the dose is given per hour)
Converting the patient's weight from pounds to kilograms:
Patient weight = 110 lb ÷ 2.2046 = 49.9 kg
Substituting the values into the formula:
Rate (mL/hr) = (2.5 g × 49.9 kg × 60) / (250 mL × 1)
Simplifying the equation:
Rate (mL/hr) = (2.5 × 49.9 × 60) / 250
Rate (mL/hr) = 74.85
Rounding to the nearest whole number, the nurse should program the IV pump to deliver 75 mL/hr.
Therefore, the correct answer is c. 75 mL/hr.
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