Allopurinol 115 mg/m² is prescribed to a client who weighs 55 kg and is 148 cm tall. Allopurinol is supplied in vials containing 25 mg/mL after reconstitution.
How much solution should a nurse draw for one dose?
4.6 mL
5.9 mL
66.9 mL
6.49 mL
12.4 mL
The Correct Answer is D
To find the amount of solution to draw for one dose, you need to calculate the following:
- The body surface area (BSA) of the client in square meters (m²) using the formula: BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
- The dose of allopurinol in milligrams (mg) using the formula: Dose (mg) = BSA (m²) x Prescribed dose
(mg/m²)
- The volume of solution in milliliters (mL) using the formula: Volume (mL) = Dose (mg) / Concentration (mg/mL)
First, use the formula for BSA to find the client's body surface area in square meters:
BSA (m²) = √(Height (cm) x Weight (kg) / 3600)
Since the client's height is 148 cm and weight is 55 kg, plug in these values into the formula:
BSA (m²) = √(148 cm x 55 kg / 3600)
Simplify and solve for the BSA:
BSA (m²) = 1.41 m²
Next, use the formula for dose to find the amount of allopurinol in milligrams:
Dose (mg) = BSA (m²) x Prescribed dose (mg/m²)
Since the client's BSA is 1.41 m² and the prescribed dose is 115 mg/m², plug in these values into the formula:
Dose (mg) = 1.41 m² x 115 mg/m²
Simplify and solve for the dose:
Dose (mg) = 162.15 mg
Then, use the formula for volume to find the amount of solution in milliliters:
Volume (mL) = Dose (mg) / Concentration (mg/mL)
Since the dose is 162.15 mg and the concentration is 25 mg/mL, plug in these values into the formula:
Volume (mL) = 162.15 mg / 25 mg/mL
Simplify and solve for the volume:
Volume (mL) = 6.486 mL
Therefore, the nurse should draw **6.486 mL** of solution for one dose of allopurinol.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
The instruction that should be given to this client for the effective management of hypertension is to take
**five tablets** of bisoprolol per day, each containing 100 mg.
This is because the new order of 500 mg of bisoprolol per day is twice as much as the current dose of 250 mg of bisoprolol per day (two and a half tablets of 100 mg each). Therefore, the client needs to double the number of tablets they take per day from two and a half to five.
Correct Answer is B
Explanation
This is another dosage calculation problem. To solve it, we need to use the formula:
Caloric need ÷ Calories per mL 1000 = Formula per day
In this case, the caloric need is 2250 calories, and the calories per mL is 2000/1000 = 2. Plugging these values into the formula, we get:
2250 ÷ 2 × 1000 = 1125
Therefore, the client would need **1125 mL** of formula per day to meet the calorie requirements.
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