After administering propylthiouracil (PTU), what effect would the nurse anticipate the drug will have in the client’s body?
To suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).
To suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).
To inhibit production of thyroid hormone in the thyroid gland.
To destroy part of the thyroid gland.
The Correct Answer is C
Propylthiouracil (PTU) is an antithyroid drug that blocks the synthesis of thyroid hormones by interfering with the oxidation of iodine and the coupling of iodotyrosines.
This reduces the levels of triiodothyronine (T) and thyroxine (T) in the blood and relieves the symptoms of hyperthyroidism.
Choice A is wrong because PTU does not destroy any part of the thyroid gland.
It only inhibits the production of thyroid hormones within the gland.
Choice B is wrong because PTU does not suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).
TSH is a hormone that stimulates the thyroid gland to produce thyroid hormones.
PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.
Choice D is wrong because PTU does not suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).
TRH is a hormone that stimulates the pituitary gland to secrete TSH.
PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.
Normal ranges for T are 80 to 220 ng/dL, for T are 4.5 to 11.2 mcg/dL, and for TSH are 0.4 to 4.0 mIU/L.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
This is an antithyroid medication that can be used safely during pregnancy, as it has a lower risk of causing birth defects or fetal hypothyroidism than other drugs. Propylthiouracil inhibits the synthesis of thyroid hormones and also blocks their conversion to the more active form.
Choice A is wrong because radioactive iodine is contraindicated during pregnancy, as it can cross the placenta and damage the fetal thyroid gland.
Radioactive iodine is used to destroy overactive thyroid cells and treat hyperthyroidism.
Choice B is wrong because alendronate is not an antithyroid medication, but a bisphosphonate that is used to treat osteoporosis and prevent bone loss.
Alendronate should not be used during pregnancy, as it may affect fetal bone development and mineralization.
Choice D is wrong because methimazole is another antithyroid medication, but it is not the drug of choice for pregnant women, as it has a higher risk of causing birth defects or fetal hypothyroidism than propylthiouracil.
Methimazole also inhibits the synthesis of thyroid hormones, but does not block their conversion to the more active form.
Correct Answer is A
Explanation
Diaphoresis means excessive sweating, which is one of the symptoms of hypoglycemia. Hypoglycemia occurs when the blood sugar level is lower than the normal range, which can cause dizziness, confusion, weakness, hunger, and other signs.
Choice B is wrong because flushing of the face is not a symptom of hypoglycemia.
Flushing can be caused by other conditions, such as fever, allergic reactions, or rosacea.
Choice C is wrong because fruity breath is a symptom of hyperglycemia, not hypoglycemia.
Hyperglycemia means high blood sugar level, which can cause the body to produce ketones that give the breath a fruity odor.
Choice D is wrong because unpredictable behaviors are not a specific symptom of hypoglycemia.
However, hypoglycemia can cause confusion, irritability, or anxiety, which may affect the behavior of some people.
The normal range of blood sugar level for most people is between 70 and 130 mg/dL (3.9 and 7.2 mmol/L) before meals and less than 180 mg/dL (10 mmol/L) after meals.
However, this may vary depending on the individual and the type of diabetes.
It is important to monitor the blood sugar level regularly and treat hypoglycemia promptly by eating or drinking a simple sugar source.
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