After administering propylthiouracil (PTU), what effect would the nurse anticipate the drug will have in the client’s body?

To suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).

To suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).

To inhibit production of thyroid hormone in the thyroid gland.

To destroy part of the thyroid gland.

Answer and Explanation

The Correct Answer is C

Propylthiouracil (PTU) is an antithyroid drug that blocks the synthesis of thyroid hormones by interfering with the oxidation of iodine and the coupling of iodotyrosines.

Thyroid and Antithyroid Drugs - Katzung & Trevor's Pharmacology Examination and Board Review, 9th Edition

This reduces the levels of triiodothyronine (T) and thyroxine (T) in the blood and relieves the symptoms of hyperthyroidism.

Choice A is wrong because PTU does not destroy any part of the thyroid gland.

It only inhibits the production of thyroid hormones within the gland.

Choice B is wrong because PTU does not suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).

TSH is a hormone that stimulates the thyroid gland to produce thyroid hormones.

PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.

Choice D is wrong because PTU does not suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).

TRH is a hormone that stimulates the pituitary gland to secrete TSH.

PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.

Normal ranges for T are 80 to 220 ng/dL, for T are 4.5 to 11.2 mcg/dL, and for TSH are 0.4 to 4.0 mIU/L.

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Correct Answer is B

Explanation

The nurse should caution the student to avoid using alcohol with trimethobenzamide because this combination can cause side effects such as drowsiness, dizziness, and impaired reactions. Alcohol can also worsen the symptoms of nausea and vomiting.

Choice A is wrong because St.

John’s wort is a herbal supplement that is used to treat depression and anxiety.

It does not interact with trimethobenzamide.

Choice C is wrong because calcium channel blockers are a class of medications that are used to treat high blood pressure and heart problems.

They do not interact with trimethobenzamide.

Choice D is wrong because selective serotonin reuptake inhibitors (SSRIs) are a class of medications that are used to treat depression and anxiety.

They do not interact with trimethobenzamide.

Trimethobenzamide is an antihistamine that works by blocking the D receptor in the brain and suppressing the chemoreceptor trigger zone that causes nausea and vomiting.

It is available as an oral capsule or an intramuscular injection.

It can cause side effects such as skin rash, tremors, parkinsonism, and jaundice.

It should not be used in children or people with liver or kidney disease.

A. Liver failure. B. Radiation injury. C. Malignancy. D. Hypothyroidism.

Correct Answer is C

Explanation

Hypercalcemia is a condition caused by having too much calcium in the blood, which can affect the function of nerves, muscles, kidneys and heart. Hypercalcemia can occur in children due to various causes, both acquired and genetic. One of the most common causes of hypercalcemia in children is cancer, especially cancers that affect the bones or produce substances that mimic parathyroid hormone (PTH), which regulates calcium levels.

Choice A is wrong because liver failure does not directly cause hypercalcemia, although it can affect vitamin D metabolism and calcium absorption.

Choice B is wrong because radiation injury does not cause hypercalcemia, unless it damages the parathyroid glands or causes bone destruction.

Choice D is wrong because hypothyroidism does not cause hypercalcemia, although it can affect bone turnover and calcium excretion.

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After administering propylthiouracil (PTU), what effect would the nurse anticipate the drug will have in the client’s body?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A college student with migraine headaches that cause nausea and vomiting has been prescribed trimethobenzamide. The nurse should caution the student to avoid using which substance?

Correct Answer is B

Explanation

The nurse is caring for a pediatric client with a new onset of hypercalcemia. What condition would be most likely to cause this altered serum calcium level?

Correct Answer is C

Explanation

For which client would the use of a phenothiazine most likely be contraindicated?

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