After administering propylthiouracil (PTU), what effect would the nurse anticipate the drug will have in the client’s body?
To suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).
To suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).
To inhibit production of thyroid hormone in the thyroid gland.
To destroy part of the thyroid gland.
The Correct Answer is C
Propylthiouracil (PTU) is an antithyroid drug that blocks the synthesis of thyroid hormones by interfering with the oxidation of iodine and the coupling of iodotyrosines.
This reduces the levels of triiodothyronine (T) and thyroxine (T) in the blood and relieves the symptoms of hyperthyroidism.
Choice A is wrong because PTU does not destroy any part of the thyroid gland.
It only inhibits the production of thyroid hormones within the gland.
Choice B is wrong because PTU does not suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).
TSH is a hormone that stimulates the thyroid gland to produce thyroid hormones.
PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.
Choice D is wrong because PTU does not suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).
TRH is a hormone that stimulates the pituitary gland to secrete TSH.
PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.
Normal ranges for T are 80 to 220 ng/dL, for T are 4.5 to 11.2 mcg/dL, and for TSH are 0.4 to 4.0 mIU/L.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
The nurse should ask this question because the client is taking a chemical stimulant laxative, which can cause dehydration and electrolyte imbalance, especially in combination with medications for heart failure and osteoarthritis that may also affect fluid and electrolyte balance. The nurse should assess the client’s hydration status and risk of hypovolemia or hypotension.
Choice B. Timing of medication administration is wrong because it is not the priority question in this situation.
The nurse should ask this question later to determine if the client is taking the medications as prescribed and if there are any drug interactions or adverse effects.
Choice C. Previous effectiveness of laxatives is wrong because it is not relevant to the client’s current condition.
The nurse should ask this question later to evaluate the client’s bowel habits and history of constipation.
Choice D. The amount of fiber intake is wrong because it is not the priority question in this situation.
The nurse should ask this question later to educate the client about dietary measures to prevent constipation and promote bowel health.
Correct Answer is B
Explanation
The nurse should caution the student to avoid using alcohol with trimethobenzamide because this combination can cause side effects such as drowsiness, dizziness, and impaired reactions. Alcohol can also worsen the symptoms of nausea and vomiting.
Choice A is wrong because St.
John’s wort is a herbal supplement that is used to treat depression and anxiety.
It does not interact with trimethobenzamide.
Choice C is wrong because calcium channel blockers are a class of medications that are used to treat high blood pressure and heart problems.
They do not interact with trimethobenzamide.
Choice D is wrong because selective serotonin reuptake inhibitors (SSRIs) are a class of medications that are used to treat depression and anxiety.
They do not interact with trimethobenzamide.
Trimethobenzamide is an antihistamine that works by blocking the D receptor in the brain and suppressing the chemoreceptor trigger zone that causes nausea and vomiting.
It is available as an oral capsule or an intramuscular injection.
It can cause side effects such as skin rash, tremors, parkinsonism, and jaundice.
It should not be used in children or people with liver or kidney disease.
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