After administering propylthiouracil (PTU), what effect would the nurse anticipate the drug will have in the client’s body?
To suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).
To suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).
To inhibit production of thyroid hormone in the thyroid gland.
To destroy part of the thyroid gland.
The Correct Answer is C
Propylthiouracil (PTU) is an antithyroid drug that blocks the synthesis of thyroid hormones by interfering with the oxidation of iodine and the coupling of iodotyrosines.
This reduces the levels of triiodothyronine (T) and thyroxine (T) in the blood and relieves the symptoms of hyperthyroidism.
Choice A is wrong because PTU does not destroy any part of the thyroid gland.
It only inhibits the production of thyroid hormones within the gland.
Choice B is wrong because PTU does not suppress the anterior pituitary gland’s secretion of thyroid-stimulating hormone (TSH).
TSH is a hormone that stimulates the thyroid gland to produce thyroid hormones.
PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.
Choice D is wrong because PTU does not suppress the hypothalamus’s production of thyrotropin-releasing hormone (TRH).
TRH is a hormone that stimulates the pituitary gland to secrete TSH.
PTU does not affect the feedback loop between the hypothalamus, pituitary, and thyroid glands.
Normal ranges for T are 80 to 220 ng/dL, for T are 4.5 to 11.2 mcg/dL, and for TSH are 0.4 to 4.0 mIU/L.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Diaphoresis means excessive sweating, which is one of the symptoms of hypoglycemia. Hypoglycemia occurs when the blood sugar level is lower than the normal range, which can cause dizziness, confusion, weakness, hunger, and other signs.
Choice B is wrong because flushing of the face is not a symptom of hypoglycemia.
Flushing can be caused by other conditions, such as fever, allergic reactions, or rosacea.
Choice C is wrong because fruity breath is a symptom of hyperglycemia, not hypoglycemia.
Hyperglycemia means high blood sugar level, which can cause the body to produce ketones that give the breath a fruity odor.
Choice D is wrong because unpredictable behaviors are not a specific symptom of hypoglycemia.
However, hypoglycemia can cause confusion, irritability, or anxiety, which may affect the behavior of some people.
The normal range of blood sugar level for most people is between 70 and 130 mg/dL (3.9 and 7.2 mmol/L) before meals and less than 180 mg/dL (10 mmol/L) after meals.
However, this may vary depending on the individual and the type of diabetes.
It is important to monitor the blood sugar level regularly and treat hypoglycemia promptly by eating or drinking a simple sugar source.
Correct Answer is A
Explanation
Desmopressin is a synthetic analog of antidiuretic hormone (ADH) that acts on the kidneys to increase water reabsorption and decrease urine output. Neurogenic diabetes insipidus is a condition caused by a deficiency of ADH due to damage to the hypothalamus or pituitary gland. Patients with this condition have excessive thirst and urination, dehydration, and low urine specific gravity.
Choice B. Methylprednisolone is wrong because it is a corticosteroid that suppresses inflammation and immune response.
It is not used to treat diabetes insipidus.
Choice C. Dexamethasone is wrong because it is also a corticosteroid that has similar effects as methylprednisolone.
It is not used to treat diabetes insipidus.
Choice D. Physostigmine is wrong because it is a cholinesterase inhibitor that increases the levels of acetylcholine in the body.
It is used to treat myasthenia gravis and anticholinergic poisoning.
It has no effect on diabetes insipidus.
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