A patient with alcoholic liver disease has severe anemia. Which of the following explains the development of anemia in this particular patient?
Alcohol suppresses erythropoiesis.
Alcoholics are often deficient in folate.
Liver dysfunction leads to decreased clotting factors.
Gastric ulcers may lead to chronic blood loss.
Alcohol causes inflammation, which leads to anemia.
The Correct Answer is A
A. Alcohol can directly suppress the production of red blood cells (erythropoiesis) in the bone marrow, leading to anemia.
B. While alcoholics may indeed be deficient in folate due to poor nutrition, folate deficiency is not the primary mechanism for anemia in alcoholic liver disease.
C. Liver dysfunction can lead to decreased production of clotting factors, contributing to coagulopathy, but it is not the primary mechanism for anemia in alcoholic liver disease.
D. Gastric ulcers may indeed lead to chronic blood loss, contributing to anemia, but it is not specific to alcoholic liver disease.
E. While alcohol-induced inflammation may contribute to various complications, including liver damage, it is not the primary mechanism for anemia in alcoholic liver disease.
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Related Questions
Correct Answer is C
Explanation
A. Gastrointestinal bleeding is a common source of chronic blood loss leading to iron deficiency anemia.
B. Peptic ulcers can cause chronic gastrointestinal bleeding, contributing to iron deficiency.
C. Loss of intrinsic factor leads to vitamin B12 deficiency and pernicious anemia, not iron deficiency.
D. Genitourinary bleeding is another potential source of chronic blood loss that can result in iron deficiency anemia.
Correct Answer is B
Explanation
A. Diarrhea: While diarrhea can occur in some cases of ovarian cancer, it is not one of the most common manifestations.
B. Unexplained weight loss: Unexplained weight loss is a common symptom of ovarian cancer and may be due to factors such as cancer-related cachexia or decreased appetite.
C. Urinary retention: Urinary retention is not a typical manifestation of ovarian cancer. Urinary symptoms may occur if the cancer spreads to nearby structures, but urinary retention is not
common.
D. Abdominal bloating: Abdominal bloating is a common symptom of ovarian cancer, often accompanied by feelings of fullness and increased abdominal girth. It is often one of the earliest and most noticeable symptoms of the disease.
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