A patient will be starting therapy with a corticosteroid. The nurse reviews the prescriber's orders and notes that an interaction may occur if the corticosteroid is taken with which of these drug classes?
Antibiotics
Nonsteroidal anti-inflammatory drugs
Opioid analgesics
Antidepressants
The Correct Answer is B
Choice A reason: Antibiotics are not likely to interact with corticosteroids, unless they are aminoglycosides, which can increase the risk of hypokalemia. However, most antibiotics do not affect the metabolism or efficacy of corticosteroids.
Choice B reason: Nonsteroidal anti-inflammatory drugs (NSAIDs) can interact with corticosteroids, as they both have anti-inflammatory and immunosuppressive effects. This can increase the risk of gastrointestinal bleeding, ulceration, and perforation. Therefore, the nurse should monitor the patient for signs of bleeding and advise the patient to avoid taking NSAIDs with corticosteroids.
Choice C reason: Opioid analgesics are not likely to interact with corticosteroids, unless they are codeine, which can decrease the clearance of corticosteroids. However, most opioid analgesics do not affect the metabolism or efficacy of corticosteroids.
Choice D reason: Antidepressants are not likely to interact with corticosteroids, unless they are monoamine oxidase inhibitors (MAOIs), which can increase the risk of hypertension and hypertensive crisis. However, most antidepressants do not affect the metabolism or efficacy of corticosteroids.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: This is incorrect because insulin can be given intravenously in certain situations, such as diabetic ketoacidosis, hyperglycemic hyperosmolar state, or perioperative care.
Choice B reason: This is correct because regular insulin is the only type of insulin that can be administered intravenously, as it is a short-acting insulin that has a rapid onset and peak. Other types of insulin, such as intermediate-acting or long-acting, are not suitable for intravenous use, as they have a delayed onset and peak and may cause hypoglycemia.
Choice C reason: This is incorrect because insulin aspart and insulin lispro are rapid-acting insulins that have a faster onset and peak than regular insulin. They are not recommended for intravenous use, as they may cause severe hypoglycemia. They are usually given subcutaneously before meals to control postprandial blood glucose levels.
Choice D reason: This is incorrect because not all forms of insulin can be administered intravenously, as explained above. Only regular insulin can be given intravenously, and the dose may differ from the subcutaneous dose depending on the patient's blood glucose level and insulin sensitivity.
Correct Answer is B
Explanation
Choice A reason: This is incorrect because the patient may not see a response from the medication for at least six months. The patient should continue taking the medication as prescribed and follow up with the provider regularly.
Choice B reason: This is correct because finasteride can cause birth defects in male fetuses if it is absorbed through the skin or ingested by pregnant women. The patient should wear gloves when handling the tablets and avoid contact with crushed or broken tablets.
Choice C reason: This is incorrect because PSA levels will decrease while taking this medication. PSA stands for prostate-specific antigen, which is a marker for prostate cancer. The patient should inform the provider that they are taking finasteride before having a PSA test, as it may affect the results.
Choice D reason: This is incorrect because grapefruit juice does not interact with finasteride. However, the patient should avoid alcohol and other medications that may affect the liver while taking finasteride.
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