A patient is admitted for acute renal failure and the nurse is monitoring their response to medications. Which pharmacokinetic principle does the nurse understand will most likely be affected in this patient?

A nurse is preparing to administer ceftriaxone 250 mg IM to an adult client who has a gonococcal infection. The label on the vial indicates to reconstitute each vial with sterile water 2.1 mL to yield ceftriaxone 350 mg/mL. How many mL of the reconstituted medication should the nurse administer? (Round the answer to the nearest hundredth. Use a leading zero if it applies. Do not use a trailing zero.)

A nurse is preparing to administer ampicillin 500 mg IM every 6 hr. Available is ampicillin 500 mg vial. The package insert instructs adding 1.8 mL of sterile water to yield ampicillin 250 mg/mL. How many mL should the nurse administer per dose?
(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Which of the following clients would the nurse question an order for labetalol 50 mg PO?

A nurse is preparing to administer darbepoetin 0.45 mcg/kg subcutaneous once weekly to a client who weighs 198 lb. The amount available is Darbepoetin 300 mcg/mL. How many mL should the nurse administer?
(Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

The nurse notes a client with a prescription for glipizide is confused, diaphoretic, and tachycardic. What is the nurse’s priority assessment?

Which response by the patient would indicate to the nurse that the client understood the education for their new hydrochlorothiazide prescription?

A nurse is preparing to administer megestrol 200 mg PO to a client. Available is megestrol oral suspension 40 mg/mL. How many mL should the nurse administer?
(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

A client has been hospitalized for multiple sclerosis exacerbation and is being given high dose IV glucocorticoid steroid medications. The prescriber places new orders for weight based sliding scale insulin. The patient asks why they need insulin. Are they now diabetic? What is the nurse's best response?

A nurse is preparing to administer tobramycin 3 mg/kg/day IM in three divided doses to a client who weighs 85 kg. The amount available is Tobramycin 40 mg/mL. How many mL should the nurse administer per dose?
(Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

A nurse is preparing to administer methylprednisolone sodium succinate 30 mg/kg via intermittent IV bolus to a client who weighs 169 lb. Available is methylprednisolone sodium succinate 125 mg/mL. How many mL should the nurse administer?
(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)