A parent brings a 2-week-old infant to a clinic for a phenylketonuria rescreening blood test. The test indicates a serum phenylalanine level of 1 mg/dL (60.5 mcmol/L). The nurse reviews this result and makes which interpretation?

A. Symptoms are continuous throughout the day:
Incorrect: Continuous symptoms throughout the day are more indicative of moderate or severe persistent asthma, not mild persistent asthma.
B. Daytime symptoms occur more than twice a week:
Correct Answer: Children with mild persistent asthma may experience symptoms more than twice a week, but less than once a day.
C. Peak expiratory flow (PEF) is greater than or equal to 80% of the predicted value:In mild persistent asthma, pulmonary function tests (e.g., PEF or FEV1) remain normal or close to normal, with values typically ≥80% of the predicted value, reflecting good lung function between episodes.
D. Nighttime symptoms occur approximately twice a month:
Mild persistent asthma often involves nighttime symptoms or awakenings occurring 3–4 times per month. If nighttime symptoms occur more frequently (e.g., once weekly), it suggests moderate persistent asthma.
E. Minor limitations occur with normal activity:Children with mild persistent asthma may experience minor limitations in their normal activities. These limitations are not severe and do not significantly impact daily life.

A. Changes in the voice signal the beginning of puberty.
Explanation: Changes in the voice, specifically deepening, are associated with puberty, but they typically occur later in puberty. The voice change is related to the growth of the larynx (Adam's apple) and tends to happen after other physical changes.
B. Gynecomastia commonly occurs during late puberty.
Explanation:
Gynecomastia, the development of breast tissue in males, is a common occurrence during puberty. It is often temporary and tends to happen during late puberty. The enlargement of breast tissue can be a source of concern for adolescent boys, and providing information about the normalcy and temporary nature of gynecomastia can be reassuring for both parents and boys.
C. Puberty might be delayed if scrotal changes have not occurred by the age of 11 years.
Explanation: The timing of pubertal changes can vary among individuals. While certain age ranges are provided as general guidelines, the absence of scrotal changes by a specific age does not necessarily indicate delayed puberty. Puberty is a gradual process with individual variations.
D. Growth spurts in height occur toward the end of midpuberty.
Explanation: Growth spurts in height, known as the adolescent growth spurt, typically occur during midpuberty. This phase is marked by rapid growth in height, changes in body composition, and the development of secondary sexual characteristics.