A nursing instructor is teaching a group of nursing students about antihistamines. Which statement by a student indicates an understanding of the mechanism of action of the antihistamines?

"Antihistamines block release of histamine from mast cells and basophils."

"Antihistamines block H1 receptors to prevent actions of histamine at these sites."

"H1 antagonists can bind to H1 receptors, H2 receptors, and muscarinic receptors."

"First-generation antihistamines are more selective than second-generation antihistamines."

Answer and Explanation

The Correct Answer is B

Antihistamines primarily work by blocking the H1 receptors, which are the receptors responsible for mediating the actions of histamine in the body. By blocking these receptors, antihistamines prevent or reduce the effects of histamine, such as itching, sneezing, runny nose, and watery eyes. This is the main mechanism by which antihistamines provide their therapeutic effects. "Antihistamines block release of histamine from mast cells and basophils." This statement is incorrect. Antihistamines do not block the release of histamine; instead, they block the histamine receptors to prevent the effects of histamine.

"H1 antagonists can bind to H1 receptors, H2 receptors, and muscarinic receptors." This statement is incorrect. H1 antagonists, or H1 receptor blockers, specifically bind to H1 receptors and do not have significant affinity for H2 receptors or muscarinic receptors. "First-generation antihistamines are more selective than second-generation antihistamines." This statement is incorrect. First-generation antihistamines are generally less selective and can have more sedating and anticholinergic effects compared to second-generation antihistamines, which are designed to be more selective for H1 receptors and have reduced sedative properties.

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Correct Answer is D

Explanation

Cephalosporins are similar to another group of beta-lactam antibiotics called the Penicillins. Both cephalosporins and penicillins belong to the beta-lactam class of antibiotics, which share a similar structure and mechanism of action. They inhibit bacterial cell wall synthesis by binding to specific proteins called penicillin-binding proteins (PBPs), leading to bacterial cell death. This shared mechanism of action makes cephalosporins and penicillins similar in their antibacterial effects.

On the other hand, macrolides, fluoroquinolones, and aminoglycosides are different classes of antibiotics with distinct structures and mechanisms of action. They work through different mechanisms to inhibit bacterial growth and have different spectrums of activity compared to beta-lactam antibiotics like cephalosporins and penicillins.

A. Use of acetaminophen to manage pain B. Onset of menopause C. Ultraviolet (UV) light exposure D. Family history of SLE

Correct Answer is C

Explanation

Excessive exposure to UV light, such as sunlight or tanning beds, is a known trigger for SLE exacerbations. It is important for individuals with SLE to protect their skin from the sun by wearing protective clothing, using sunscreen, and avoiding direct sunlight during peak hours. Having a family history of SLE increases the risk of developing the disease. While it is not a trigger in itself, it is an important piece of information for the client to be aware of, as it may indicate a genetic predisposition to the condition.

Acetaminophen is a commonly used over-the-counter pain reliever. While it can help manage pain associated with SLE, it is not typically considered a trigger for exacerbations. Menopause, which marks the end of a woman's reproductive years, does not directly trigger SLE exacerbations. However, hormonal changes during menopause can potentially affect disease activity in some individuals. It is important for the client to discuss any changes or concerns with their healthcare provider to manage their symptoms effectively.

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A nursing instructor is teaching a group of nursing students about antihistamines. Which statement by a student indicates an understanding of the mechanism of action of the antihistamines?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Cephalosporins are similar to another group of beta-lactam antibiotics called the?

Correct Answer is D

Explanation

The nurse caring for a client with systemic lupus erythematosus (SLE) would include which information in teaching about triggers that can result in an exacerbation of the disease?

Correct Answer is C

Explanation

Which nursing documentation demonstrates the integration of patient-centered care?

Match using the choices provided:

Which manifestations would the nurse expect for a client with a history of malignant hyperthermia (MH)? Select all that apply.

You're providing discharge instructions to a patient who will be taking a loop diuretic at home. Which statement by the patient demonstrates they did NOT understand the teaching material and requires that you reinforce some of the teaching points?

A nursing instructor is teaching a group of nursing students about antihistamines. Which statement by a student indicates an understanding of the mechanism of action of the antihistamines?

After receiving a hand-off report what assessment information is the most important and immediate concern for the nurse? Select all that apply.

The patient who is confined to bed in the supine position has gained 5 lbs. in the last 48 hours. In which area does the nurse assess skin turgor for accurate determination of dependent edema?