Related Questions
Correct Answer is C
Explanation
Choice A Reason: This is incorrect because sickle-cell anemia is a genetic disorder that affects the shape and function of the red blood cells. It is not related to the AFP level, which is a protein produced by the fetal liver and yolk sac.
Choice B Reason: This is incorrect because cardiac defects are abnormalities in the structure or function of the heart. They are not related to the AFP level, which is a marker of neural tube defects and abdominal wall defects.
Choice C Reason: This is correct because Down syndrome is a chromosomal disorder that results from an extra copy of chromosome 21. It is associated with a decreased AFP level, as well as increased levels of human chorionic gonadotropin (hCG) and unconjugated estriol (uE3).
Choice D Reason: This is incorrect because respiratory disorders are problems that affect the lungs and breathing. They are not related to the AFP level, which reflects the fetal development and integrity.
Correct Answer is B
Explanation
Choice A Reason: Nagele's rule is a formula that estimates the due date by subtracting three months from the first day of the last menstrual period and adding seven days. However, this method assumes a regular 28-day cycle and may not be accurate for women with irregular cycles or who are unsure of their last menstrual period.
Choice B Reason: Ultrasound is the most accurate method of determining the estimated due date, especially in the first trimester. Ultrasound uses sound waves to create an image of the fetus and measure its size and development. Ultrasound can also detect any abnormalities or complications that may affect the pregnancy.
Choice C Reason: Gestation wheel is a circular calendar that estimates the due date by aligning the first day of the last menstrual period with a corresponding date on the wheel. However, this method also assumes a regular 28-day cycle and may not account for variations in ovulation or implantation.
Choice D Reason: Birth calculator is an online tool that estimates the due date based on various factors such as the last menstrual period, cycle length, ovulation date, conception date, or ultrasound date. However, this method may not be reliable as it depends on the accuracy of the input data and the algorithm used by the calculator.

