A nurse learns that which of the following is the single biggest risk factor for developing cancer?

Choice A rationale:
Prednisone:
Corticosteroid that suppresses the immune system: It's crucial to consult with the primary healthcare provider (PCP) because prednisone can impair wound healing and increase the risk of infection after surgery. The PCP may need to adjust the dosage or temporarily discontinue prednisone prior to surgery.
Potential for adrenal insufficiency: Abrupt cessation of prednisone can lead to adrenal insufficiency, a life-threatening condition. The PCP will provide guidance on how to taper the medication safely before surgery.
Interaction with anesthesia: Prednisone can interact with certain anesthetic agents, potentially increasing the risk of complications. The PCP and anesthesiologist will need to coordinate care to ensure safe medication management during surgery.
Choice B rationale:
Metoprolol:
Beta-blocker that lowers blood pressure and heart rate: While metoprolol is generally safe to continue before surgery, it's still essential to inform the PCP and anesthesiologist about its use. They will monitor heart rate and blood pressure closely during and after surgery, as metoprolol can interact with certain medications used during the procedure.
Choice C rationale:
Warfarin:
Blood thinner that prevents blood clots: Warfarin requires careful management around surgery due to its significant bleeding risk. The PCP will typically recommend holding warfarin for several days before surgery to allow for normalization of blood clotting. They may also bridge with a shorter-acting anticoagulant if necessary.
Potential for bleeding complications: If warfarin is not managed appropriately, it can lead to excessive bleeding during or after surgery. The PCP will closely monitor the patient's INR (international normalized ratio), a measure of blood clotting, to ensure it's within the safe range for surgery.
Choice D rationale:
Insulin:
Hormone that regulates blood sugar: Patients with diabetes who take insulin require careful blood sugar control around surgery to prevent complications. The PCP will provide specific instructions on how to adjust insulin doses before, during, and after surgery, as insulin needs often change due to the stress of surgery and the impact of anesthesia.
Risk of hypoglycemia and hyperglycemia: Both low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia) can have serious consequences during and after surgery. The PCP will work with the patient to manage blood sugar levels and prevent these complications.
Choice E rationale:
Phenytoin:
Anticonvulsant medication that controls seizures: Phenytoin has a narrow therapeutic window, meaning that blood levels must be closely monitored to ensure efficacy and prevent toxicity. Surgery can affect phenytoin levels, so the PCP will likely recommend checking a blood level before surgery and adjusting the dose as needed.
Potential for drug interactions: Phenytoin interacts with many medications, including some commonly used during surgery. The PCP will need to review the patient's medication list carefully and make any necessary adjustments to prevent interactions.
Choice F rationale:
Omega-3 fatty acid:
Generally safe to continue before surgery: Omega-3 fatty acids are not known to have significant interactions with medications used during surgery or to pose risks for wound healing or bleeding. However, it's always best to inform the PCP about any supplements being taken.

Choice A rationale:
While it's true that dehydration can lead to incontinence, simply stating this fact to the patient doesn't directly address the issue of dehydration. It doesn't provide actionable steps to correct the dehydration.
Incontinence can be a result of dehydration, but addressing the dehydration is the primary concern to prevent further complications.
Providing information about incontinence might be helpful in other contexts, but it's not the most effective advice to address mild dehydration in this specific scenario.
Choice B rationale:
Diuretics promote fluid loss through urination, which can worsen dehydration.
Advising the patient to take a diuretic in the morning would be counterproductive in this case. The goal is to increase fluid intake, not further deplete fluid levels.
It's important to consider the patient's medications and potential interactions before suggesting any changes to their medication regimen.

Choice C rationale:
Regular fluid intake is essential for maintaining hydration and replenishing lost fluids.
This advice directly addresses the issue of dehydration by encouraging the patient to consume fluids consistently. Drinking fluids every 1 to 2 hours can help restore fluid balance and prevent further complications.
It's a simple, actionable, and effective measure to address mild dehydration.
Choice D rationale:
While reducing sodium intake can be beneficial for some individuals with hypertension or other conditions, it's not the most relevant advice for addressing mild dehydration.
Sodium restriction might be appropriate in certain cases, but it doesn't directly address the immediate need to increase fluid intake.
The primary focus in this situation should be on replenishing fluids, not restricting sodium.