A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?
Sildenafil
Gemfibrozil
Lansoprazole
Diazepam
The Correct Answer is A
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Dantrolene prevents release of calcium from the sarcoplasmic reticulum preventing the interaction of actin and myosin in the excitation-contraction coupling process. This process prevents excessive muscle contraction and slows down metabolism.
A- A calcium channel blocker
B- An opioid antagonist
C- C-An antibiotic
Correct Answer is B
Explanation
Hypoglycemia is a potential complication of parenteral nutrition, especially if the infusion rate is too high or if the infusion is interrupted. The nurse should promptly address hypoglycemia by administering IV dextrose, which will help raise the client's blood glucose levels.
A. Discontinuing the infusion may be necessary if the cause of hypoglycemia is related to the parenteral nutrition solution or if the infusion rate needs adjustment. However, the immediate priority is to treat the hypoglycemia by providing a glucose source.
C. Warming the formula to room temperature is not relevant to treating hypoglycemia. Warming the formula might be done for other reasons, such as improving tolerance or reducing discomfort during administration.
D. Obtaining arterial blood gases is not indicated for treating hypoglycemia. Arterial blood gases are typically obtained to assess oxygenation and acid-base balance, not glucose levels.
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