A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?
Sildenafil
Gemfibrozil
Lansoprazole
Diazepam
The Correct Answer is A
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
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Related Questions
Correct Answer is C
Explanation
This indicates a reduction in the abdominal swelling caused by fluid accumulation, which is a common complication of cirrhosis. Spironolactone is a diuretic that helps remove excess fluid from the body. Spironolactone in liver cirrhosis is used to reduce fluid retention and hence decrease ascites
The other effects are not directly related to spironolactone use
Correct Answer is B
Explanation
- Theophylline is used in the management of asthma and COPD which present with wheezing and respiratory distress. COPD is characterized by chronic inflammation of the airway and increased mucus secretion leading to obstruction of airflow. Theophylline stimulates the respiratory centers to increase ventilation.
A- No effect on blood pressure C- increases urine output
D-Theophylline is a CNS stimulant
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