A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?
Sildenafil
Gemfibrozil
Lansoprazole
Diazepam
The Correct Answer is A
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
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Related Questions
Correct Answer is C
Explanation
Diazepam is a benzodiazepine with potential for respiratory depression. It is, therefore, important for the nurse to cautiously monitor the respiratory rate and respond appropriately at each review.
A-Diazepam is an anticonvulsant
B, D- Diazepam has no effect on bowel habits and urinary output
Correct Answer is D
Explanation
This group of individuals is not typically contraindicated for the varicella vaccine. In fact, older adults who have not been previously vaccinated or have not had chickenpox are often encouraged to receive the vaccine.
The varicella vaccine is produced using embryonated chicken eggs. Individuals with a severe allergy to eggs (such as anaphylaxis) should avoid this vaccine. However, most people with mild egg allergies can safely receive it. A healthcare provider should assess the severity of the egg allergy before making a decision.
There is no known contraindication between the varicella vaccine and the human papillomavirus (HPV) vaccine. These vaccines target different infections and can be administered independently.
Individuals with advanced immunosuppression, including those with AIDS, should not receive the varicella vaccine. Their weakened immune system may not respond effectively to the vaccine, and there is a risk of disseminated varicella infection.
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