A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?
Sildenafil
Gemfibrozil
Lansoprazole
Diazepam
The Correct Answer is A
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
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Related Questions
Correct Answer is D
Explanation
The term PRN stands for when needed which does not state the specific circumstances under which the medication should be given. It is therfore, important to confirm tis to ensure safe administration of the medication
Correct Answer is D
Explanation
Melena means that the stool has a dark discoloration. This is a sign of gastrointestinal bleeding and should be reported immediately as it can be a serious complication of warfarin therapy.
A,B,C- Are not related to use of warfarin
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