A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?
Sildenafil
Gemfibrozil
Lansoprazole
Diazepam
The Correct Answer is A
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","D","E","F"]
Explanation
The medication causes a harmless discoloration or urine (Levodopa causes darkening of urine rather than lightening), high protein intake interferes with the availability of the medication in the CNS, The medication causes orthostatic hypotension and dizziness, The medication should be taken with a meal if nausea and vomiting occurs, Initially the medication can cause dyskinesia which should be reported, The medication also cause hallucinations and sleep disturbances
Correct Answer is D
Explanation
Respiratory rate of 10/min indicates respiratory depression which a potential adverse effect of morphine. Opioids suppress the central respiratory centers leading to respiratory depression. Use of two opioids increases their levels in blood raising the risk of respiratory depression even higher which is fatal.
A.- Elevated blood pressure is not directly related to morphine use . Could be an indication of pain
B.-Normal temperature
C.-Normal heart rate
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