A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?

Sildenafil

Gemfibrozil

Lansoprazole

Diazepam

Answer and Explanation

The Correct Answer is A

Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin

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Correct Answer is B

Explanation

Propofol causes positive modulation of the inhibitory function of the neurotransmitter gamma-aminobutyric acid (GABA) through GABA-A receptors. It also enhances GABA's effects leads to increased chloride influx into neurons, causing hyperpolarization and decreased neuronal activity. This results in the sedative and hypnotic effects for which propofol is used during anesthesia. Propofol can cause respiratory depression when levels in the blood are high and hence respiratory rate should be monitored closely

A-Propofol is likely to cause bradycardia due to depression of central cardiac centers

C-Propofol has no effect on bowel function

D-Propofol can cause hypothermia when used in anesthesia but not as critical as respiratory depression

A. "Pour expired medication tablets into a waste basket." B. "Discard expired medication down the toilet." C. "Crush expired medication tablets and rinse them down the sink." D. "Return expired medication to the pharmacist."

Correct Answer is D

Explanation

Returning the mediation to the pharmacy allows for safe disposal A,B,C- Could lead to environmental contamination with potential hazards

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A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is caring for a client who has received propofol during a colonoscopy. The nurse should monitor for which of the following as an adverse effect of the medication?

Correct Answer is B

Explanation

A home care nurse is teaching a client about safe medication disposal. Which of the following instructions should the nurse include?

Correct Answer is D

Explanation

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