A nurse is reviewing the laboratory results of a client with severe pre-eclampsia who is receiving magnesium sulfate.
Which finding would indicate a therapeutic level of magnesium sulfate?
Serum magnesium level of 4.5 mEq/L
Serum calcium level of 8.5 mg/dL
Serum creatinine level of 1.2 mg/dL
Serum potassium level of 3.5 mEq/L
The Correct Answer is A
This indicates a therapeutic level of magnesium sulfate for a client with severe pre-eclampsia who is receiving magnesium sulfate. According to some sources, the effective therapeutic serum magnesium level is 1.8–3.0 mmol/L, which corresponds to 4.2–7 mg/dL or 3.5–7 mEq/L.

Choice B is wrong because serum calcium level of 8.5 mg/dL is within the normal range and does not indicate the effect of magnesium sulfate.
Choice C is wrong because serum creatinine level of 1.2 mg/dL is within the normal range and does not indicate the effect of magnesium sulfate.
Choice D is wrong because serum potassium level of 3.5 mEq/L is at the lower end of the normal range and does not indicate the effect of magnesium sulfate.
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Correct Answer is D
Explanation
This is the rationale for using this medication in a client with pre-eclampsia who has a blood pressure of 180/110 mmHg.High blood pressure in pre-eclampsia can cause damage to the kidneys, liver, brain, and other organs, and can also increase the risk of complications for the baby.
Therefore, lowering blood pressure with hydralazine can help prevent or reduce these adverse outcomes.

Choice A is wrong because hydralazine does not reduce cerebral edema or prevent seizures.These are symptoms of eclampsia, a more severe form of pre-eclampsia that requires different treatment.
Choice B is wrong because hydralazine does not increase uteroplacental perfusion or fetal oxygenation.These are affected by other factors such as the placental function, maternal position, and fetal well-being.
Choice C is wrong because hydralazine does not decrease proteinuria or prevent renal damage.
Proteinuria is a sign of kidney impairment that occurs in pre-eclampsia, but it is not directly affected by hydralazine.Renal damage can be prevented by controlling blood pressure and avoiding nephrotoxic drugs.
Correct Answer is C
Explanation
This is because bed rest can lower blood pressure and improve blood flow to the placenta and the fetus.The left lateral position reduces pressure on the inferior vena cava, a large vein that carries blood from the lower body to the heart.
Choice A is wrong because magnesium sulfate is used to prevent seizures in severe preeclampsia or eclampsia, not mild preeclampsia.
Choice B is wrong because monitoring the fetal heart rate and movement is important, but not the priority for this client.
Choice D is wrong because educating the client about the signs of eclampsia is not urgent and may not prevent the progression of preeclampsia.Some signs of eclampsia are severe headaches, blurred vision, nausea, vomiting, abdominal pain and seizures.
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