A nurse is reviewing the BUN result of a client who is taking cyclosporine following a kidney transplant. Which of the following laboratory studies should the nurse recognize as another renal function study that should be monitored?
Bilirubin
Alkaline phosphatase
Amylase
Creatinine
The Correct Answer is D
Choice A reason: Bilirubin assesses liver function, not kidneys. Cyclosporine’s nephrotoxicity affects glomerular filtration, not heme metabolism. Monitoring bilirubin is irrelevant for renal function in transplant clients, as it reflects hepatic or hemolytic processes, not kidney health or drug toxicity.
Choice B reason: Alkaline phosphatase evaluates liver or bone health, not kidneys. Cyclosporine may cause hepatotoxicity, but renal monitoring is critical due to its nephrotoxic potential. Alkaline phosphatase does not reflect glomerular or tubular function, making it unsuitable for assessing renal impact.
Choice C reason: Amylase measures pancreatic function, not kidneys. Cyclosporine’s nephrotoxicity affects renal filtration, not pancreatic enzymes. Monitoring amylase is irrelevant for kidney transplant clients, as it does not indicate renal impairment or cyclosporine’s toxic effects on kidney function.
Choice D reason: Creatinine is a key renal function marker, reflecting glomerular filtration rate. Cyclosporine’s nephrotoxicity elevates creatinine, indicating kidney damage. Monitoring it with BUN ensures early detection of renal impairment, guiding dose adjustments to prevent further injury in transplant clients.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","D","E"]
Explanation
Choice A reason: Instructing pregnant visitors to stay 3 feet away is insufficient, as radiation from a sealed implant requires greater distance (typically 6 feet) or complete avoidance. Pregnant individuals should not visit to minimize fetal exposure, making this precaution inadequate and incorrect for safety.
Choice B reason: Wearing a lead apron shields the nurse from radiation exposure during close contact with the sealed implant, adhering to ALARA (As Low As Reasonably Achievable) principles. This protects the nurse while providing care, making it a necessary and correct safety measure.
Choice C reason: Placing the client in a semi-private room is unsafe, as radiation from the implant could expose other patients. A private room is required to minimize radiation risk to others, making this action incorrect and against radiation safety protocols.
Choice D reason: Closing the client’s door reduces radiation exposure to others outside the room, as sealed implants emit continuous radiation. This containment measure, combined with signage, ensures safety for staff and visitors, making it a correct and essential action.
Choice E reason: Limiting visitors to 30 minutes per day minimizes cumulative radiation exposure, protecting visitors from the sealed implant’s emissions. Time restrictions are standard in radiation safety protocols, ensuring minimal risk while allowing controlled visits, making this a correct action.
Correct Answer is A
Explanation
Choice A reason: Increased energy and motivation signal improvement in major depressive disorder, countering fatigue and anhedonia. Serotonin and norepinephrine rebalance, often from treatment, restores drive and engagement, reflecting neurochemical stabilization in the brain’s limbic system, critical for mood regulation and recovery.
Choice B reason: Self-doubt in decision-making reflects persistent depressive symptoms, like low self-esteem and cognitive impairment. Negative thought patterns, driven by altered prefrontal cortex activity, indicate ongoing depression, not improvement, requiring adjusted interventions to address these neurocognitive deficits in major depressive disorder.
Choice C reason: Sleeping 12 hours daily indicates hypersomnia, a depressive symptom, suggesting no improvement. Disrupted circadian rhythms and serotonin dysregulation cause excessive sleep, contrasting with recovery signs like normalized sleep patterns. This reflects persistent neurochemical imbalances hindering mood stabilization in depression.
Choice D reason: Social isolation is a core depressive symptom, driven by anhedonia and low mood, indicating no improvement. Withdrawal reflects ongoing dopamine and serotonin imbalances, preventing social engagement. Recovery involves increased interaction, making isolation a sign of persistent major depressive disorder.
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