A nurse is providing teaching to a female client who is taking conjugated equine estrogens (Premarin). Which of the following clients are contraindicated for conjugated equine estrogens (Premarin)? (Select All That Apply).
A client with a history of thromboembolic disease,
A client within story of hypertension
A client with history of depression
A client with atypical vaginal bleeding that is not diagnose
Correct Answer : A,D
A. A client with a history of thromboembolic disease: Estrogen therapy is contraindicated in clients with a history of thromboembolic disease due to the increased risk of blood clots.
B. A client with a history of hypertension: Hypertension is a relative contraindication, but it may still be prescribed with caution.
C. A client with a history of depression: Depression is not a contraindication to estrogen therapy.
D. A client with atypical vaginal bleeding that is not diagnosed: Unexplained vaginal bleeding should be investigated before administering estrogen therapy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Loperamide (Imodium): This is an anti-diarrheal medication and does not protect mucosal ulcers.
B. Cimetidine (Tagamet HB): Cimetidine is an H2 blocker used to reduce stomach acid, but it does not form a protective barrier like sucralfate.
C. Docusate sodium (Colace): This is a stool softener and is not used for protecting gastric ulcers.
D. Sucralfate (Carafate): Sucralfate is a mucosal protectant that binds to the ulcer and creates a protective barrier, preventing further injury from stomach acid and pepsin.
Correct Answer is D
Explanation
A. Excretion is the removal of the drug from the body, typically through the kidneys, and is not related to changes in the drug's potency or solubility.
B. Absorption is the process of the drug entering the bloodstream, not a process that alters the drug's chemical form.
C. Distribution is the process by which the drug is spread throughout the body’s tissues and organs, not
the phase where the drug is altered.
D. Metabolism, primarily occurring in the liver, involves the conversion of drugs into more water-soluble forms, which can either increase or decrease their potency.
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