A nurse is preparing to infuse 1 liter of 0.9% sodium chloride IV over 8 hr with a tubing set that delivers 15 gtts/mL. The nurse should set the manual IV infusion to deliver how many drops/min? Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.

Choice A Reason: This is incorrect because sickle-cell anemia is a genetic disorder that affects the shape and function of the red blood cells. It is not related to the AFP level, which is a protein produced by the fetal liver and yolk sac.

Choice B Reason: This is incorrect because cardiac defects are abnormalities in the structure or function of the heart. They are not related to the AFP level, which is a marker of neural tube defects and abdominal wall defects.

Choice C Reason: This is correct because Down syndrome is a chromosomal disorder that results from an extra copy of chromosome 21. It is associated with a decreased AFP level, as well as increased levels of human chorionic gonadotropin (hCG) and unconjugated estriol (uE3).

Choice D Reason: This is incorrect because respiratory disorders are problems that affect the lungs and breathing. They are not related to the AFP level, which reflects the fetal development and integrity.

Choice A Reason: Trisomy numeric abnormality. Down syndrome is a genetic disorder that occurs when a person has three copies of chromosome 21 instead of two. This extra chromosome causes various physical and mental features that vary from person to person. Down syndrome is also called trisomy 21 because it involves three copies of chromosome 21.

Choice B Reason: Multifactorial inheritance is incorrect because it refers to a type of genetic disorder that results from the interaction of multiple genes and environmental factors. Examples of multifactorial disorders include cleft lip or palate, neural tube defects, diabetes, hypertension, and some types of cancer.

Choice C Reason: X-linked recessive inheritance is incorrect because it refers to a type of genetic disorder that affects males more than females because it is caused by a mutation on the X chromosome. Females have two X chromosomes, so they can be carriers or affected depending on whether they inherit one or two copies of the mutated gene. Males have one X chromosome and one Y chromosome, so they are always affected if they inherit the mutated gene from their mother. Examples of X-linked recessive disorders include hemophilia, color blindness, and Duchenne muscular dystrophy.

Choice D Reason: Chromosomal deletion is incorrect because it refers to a type of genetic disorder that occurs when a part of a chromosome is missing or deleted. This can cause various physical and mental problems depending on the size and location of the deletion. Examples of chromosomal deletion