A nurse is preparing to educate a patient who has newly been prescribed sucralfate (Carafate) for the management of peptic ulcer disease (PUD). What is the mechanism of action for this medication?
Neutralizes the acidity of the gastric acid.
Acts as an endogenous prostaglandin in the GI tract.
Antagonizes H2 receptors on parietal cells.
Creates a protective barrier that adheres to an ulcer, which can stick to the ulcer for up to 6 hours.
The Correct Answer is D
A. Sucralfate does not neutralize gastric acid; antacids are responsible for neutralization.
B. Sucralfate does not mimic endogenous prostaglandins. Medications like misoprostol act as prostaglandins to protect the stomach lining.
C. Sucralfate does not block H2 receptors. Medications like cimetidine or ranitidine work through this mechanism to reduce acid production.
D. Sucralfate creates a viscous, protective barrier that adheres to the ulcer site, shielding it from further damage by gastric acid, bile, and pepsin for up to 6 hours, thereby promoting healing.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C"]
Explanation
A. "I should apply this patch behind my ear.": This is correct because the scopolamine patch is designed to be applied behind the ear, where it can effectively deliver medication through the skin.
B. "This patch should be replaced every 7 days.": This is incorrect because the scopolamine patch should be replaced every 72 hours (3 days), not every 7 days.
C. "I should not use a second patch if the initial patch is ineffective.": This is correct because using more than one patch at a time can lead to an overdose of the medication, which can cause serious side effects.
D. "Before putting on my patch, I should wipe the area with an alcohol swab.": This is incorrect because using an alcohol swab can irritate the skin and affect the absorption of the medication. The area should be clean and dry, but not cleaned with alcohol.
Correct Answer is B
Explanation
A. Glucagon is not used to treat thyroid cancer; treatments for thyroid cancer often include radioactive iodine therapy or surgery.
B. Glucagon is used to treat severe hypoglycemia in diabetic patients when they are unable to take oral glucose. It works by stimulating the liver to release stored glucose into the bloodstream, rapidly raising blood sugar levels.
C. Diabetes insipidus involves a deficiency of antidiuretic hormone or kidney insensitivity to it and is treated with desmopressin or adequate hydration, not glucagon.
D. Type 2 diabetes mellitus is typically managed with lifestyle changes, oral antidiabetic agents, or insulin. Glucagon is not used for routine management but is reserved for severe hypoglycemia emergencies.
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