A nurse is preparing to administer gentamicin to a child who weighs 44 lb. The provider prescribes 6 mg/kg/day IV to be administered in three equal doses. Available is gentamicin 40 mg/mL. How many mL should the nurse administer with each dose?

(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Choice A rationale:

Increased temperature is not a direct indication of naloxone’s effectiveness. Naloxone works by reversing the effects of opioids, which do not typically include fever.

Choice B rationale:

While naloxone can cause an abrupt withdrawal in opioid-dependent individuals, leading to symptoms such as hypertension, it does not typically decrease blood pressure in opioid overdose cases.

Choice C rationale:

Naloxone works by reversing the life-threatening depression of the central nervous system and respiratory system caused by an opioid overdose. Therefore, an increased respiratory rate after administration would indicate that the medication is effective.

Choice D rationale:

Naloxone reverses the effects of opioids, including pain relief. Therefore, a report of decreased pain would not indicate that the medication is effective.

Step 1: Convert the child's weight from pounds to kilograms.

44 pounds / 2.2 pounds/kg = 20 kg

Step 2: Calculate the child's total daily dose of gentamicin.

20 kg * 6 mg/kg/day = 120 mg/day

Step 3: Divide the child's total daily dose of gentamicin by the number of doses per day.

120 mg / 3 doses/day = 40 mg/dose

Step 4: Calculate the volume of gentamicin to be administered with each dose.

40 mg / 40 mg/mL = 1 mL/dose

Step 5: Round the answer to the nearest whole number and add a leading zero if necessary.

1 mL/dose = 1 mL/dose

Answer: 1 mL with each dose.