A nurse is evaluating a client who is 70 years old for signs of dehydration.

Which of the following findings should the nurse expect?

The correct answer is A.

Adverse drug reactions.

Polypharmacy, which refers to the effects of taking multiple medications concurrently to manage coexisting health problems, is common among older adults.

It is defined as the regular use of at least five medications.

Polypharmacy can lead to an increase in geriatric syndromes, decrease in functional outcomes, and increased mortality.

One of the major risks of polypharmacy is adverse drug reactions, which are harmful or unintended effects of a medication that occur at normal doses.

Adverse drug reactions can result from drug-drug interactions, drug-disease interactions, drug-age interactions, or inappropriate prescribing.

Adverse drug reactions can cause symptoms such as confusion, dizziness, falls, bleeding, or organ damage.

They can also lead to hospitalizations, increased health care costs, and reduced quality of life.

Choice B is wrong because medication adherence, which is the extent to which patients take medications as prescribed by their health care providers, can actually decrease with polypharmacy.

This is because taking multiple medications can be complex, costly, and burdensome for older adults, especially if they have cognitive impairment or low health literacy.

Medication adherence can also be influenced by patients’ beliefs, preferences, and expectations about their medications.

Choice C is wrong because drug-drug interactions are not a risk of polypharmacy per se, but rather a cause of adverse drug reactions.

Drug-drug interactions occur when two or more drugs affect each other’s pharmacokinetics (absorption, distribution, metabolism, excretion) or pharmacodynamics (mechanism of action, efficacy, toxicity).

Drug-drug interactions can alter the therapeutic effects or safety of a medication.

Choice D is wrong because therapeutic effects are the intended or desired effects of a medication that benefit the patient’s health condition.

Therapeutic effects can decrease with polypharmacy due to drug-drug interactions that reduce the efficacy of a medication.

Therapeutic effects can also be diminished by prescribing cascade, which is a phenomenon where a new medication is prescribed to treat a symptom that is actually an adverse drug reaction of another medication.

Normal ranges for blood pressure are.

≤120/80.

mmHg for normal,.

120−129/80.

mmHg for elevated,.

130−139/80−89.

mmHg for stage 1 hypertension, and.

≥140/90.

mmHg for stage 2 hypertension.

The correct answer is A.

HRT can relieve hot flashes, vaginal dryness and mood swings, but it can also increase the risk of breast cancer, stroke and blood clots.This answer is based on the evidence from various studies that have shown the benefits and risks of HRT.

Choice B is wrong because HRT cannot prevent osteoporosis, heart disease and dementia, and it does not cause weight gain, acne and hair loss.These are common misconceptions about HRT that are not supported by scientific research.

Choice C is wrong because HRT does not have a significant effect on sexual function, skin elasticity and memory, and it does not lower the immune system, blood pressure and blood sugar.These are also myths about HRT that have no basis in reality.

Choice D is wrong because HRT can improve sleep quality, energy levels and mood, but it can also cause or worsen headaches, nausea and bloating.These are some of the possible side effects of HRT that vary depending on the type, dose and duration of the therapy.

Normal ranges for estrogen and progesterone levels depend on the stage of menopause, the type of HRT and the individual factors of each woman.

Generally, estrogen levels range from 10 to 50 pg/mL (picograms per milliliter) and progesterone levels range from 0.1 to 25 ng/mL (nanograms per milliliter) in postmenopausal women.