A nurse is educating a group of clients about the contraindications of warfarin therapy. Which of the following statements should the nurse include in the teaching?

"Clients who have glaucoma should not take warfarin."

"Clients who have rheumatoid arthritis should not take warfarin."

"Clients who are pregnant should not take warfarin."

"Clients who have hyperthyroidism should not take warfarin."

Answer and Explanation

The Correct Answer is C

Warfarin is a coumarin anticoagulant that has potential to increase the risk of bleeding. When taken during pregnancy, warfarin causes fetal bleeding. Warfarin is also teratogenic and it causes various birth defects including skeletal abnormalities, hypoplastic nose, intellectual disabilities and deafness hence it's contraindicated. Pregnant women who require anticoagulation are put of heparin in the place of warfarin to prevent these complications.
A. B, D - are not contraindications for warfarin use.

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Correct Answer is B

Explanation

A. Diluting phenytoin with sterile water before injecting is not recommended, as phenytoin is incompatible with most used diluents. Diluting it can lead to precipitation and potentially cause adverse effects such as tissue irritation and phlebitis.
B. Administering the medication over 1 min is recommended. Phenytoin should be administered at a rate of 50mg/min.
C. Following the IV injection with sterile water is unnecessary and not indicated for administering phenytoin.
D.Phenytoin precipitates out of solution when mixed with certain diluents or when administered too quickly. Crystallized phenytoin can cause local irritation, tissue damage, and potentially more serious adverse effects. Therefore, it should not be administered at all.

A. Finasteride B. Leuprolide C. Cyclophosphamide D. Tamoxifen

Correct Answer is B

Explanation

Testosterone acts of the prostatic tissue leading to abnormal/dysplastic tissue hyperplasia and hypertrophy in prostatic cancer. Leuprolide is a gonadotropin-releasing hormone (GnRH) agonists. It suppresses the release of testosterone which is necessary for enlargement of prostatic tissue.

A. Finasteride is a 5-alpha reductase used in the management of benign prostatic hyperplasia which is not cancerous

C. Cyclophosphamide is a chemotherapeutic agent used in other cancers but not prostate cancer

D. Tamoxifen is a selective estrogen receptor modulator used in the treatment of breast cancer.

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A nurse is educating a group of clients about the contraindications of warfarin therapy. Which of the following statements should the nurse include in the teaching?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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Explanation

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Explanation

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