A nurse is discussing gout with a patient who is concerned about developing the disorder. Which of the following findings should the nurse identify as risk factors for this disease? Select all that applies.
Depression
Deep sleep deprivation
Cardiovascular disease
Diuretic use
Correct Answer : C,D
Cardiovascular disease (CVD) is a significant risk factor for gout. This is because CVD often coexists with other conditions that can elevate uric acid levels, such as hypertension, obesity, and chronic kidney disease. Additionally, some medications used to treat CVD, such as thiazide diuretics, can also increase uric acid levels.
Research has shown that people with CVD have a 2-3 times higher risk of developing gout compared to those without CVD.
The mechanisms linking CVD and gout are complex and not fully understood, but they likely involve shared pathways of inflammation and endothelial dysfunction.
Choice D rationale:
Diuretic use, particularly thiazide diuretics, is a well-established risk factor for gout. These medications work by increasing the excretion of fluids and electrolytes from the body, which can also lead to a decrease in the excretion of uric acid.
This can result in a buildup of uric acid in the blood, which can then crystallize in joints and cause gout attacks.
The risk of gout associated with diuretic use is dose-dependent, meaning that higher doses of diuretics are associated with a higher risk of gout.
Choice A rationale:
Depression has not been consistently shown to be an independent risk factor for gout. Some studies have suggested a possible link between depression and gout, but others have not found any association. More research is needed to clarify the relationship between these two conditions.
Choice B rationale:
Deep sleep deprivation has not been studied as a risk factor for gout. There is currently no evidence to suggest that it is directly associated with an increased risk of developing the disease.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["8"]
Explanation
Step 1: Determine the desired dose in mL.
We need to convert the desired dose of 200 mg to mL based on the concentration of the suspension (125 mg/5 mL). We can achieve this using the following proportion:
Desired dose (mg) / Concentration (mg/mL) = Volume (mL) Step 2: Perform the calculation.
Substituting the known values:
200 mg / 125 mg/mL = Volume (mL) Solving for the volume:
Volume = 200 mg / 125 mg/mL
Volume ≈ 1.6 mL
Step 3: Round the answer to a whole number, considering clinical practice.
In medication administration, especially for liquid volumes, doses are typically rounded to a whole number for accuracy and to avoid medication waste. Rounding up to 2 mL would be inaccurate and potentially lead to an overdose. Therefore, we round down to the nearest whole number, which is 1 mL.
Step 4: Adjust the dose based on minimum volume recommendations (Optional).
Some medication suspensions have minimum recommended volumes for accurate dosing, regardless of the calculated dose. Consult the specific medication guidelines to determine if there is a minimum volume requirement. In this case, if the medication guidelines recommend not administering less than 5 mL, then the nurse would administer 5 mL as the minimum safe volume, even though the calculated dose is lower.
Therefore, based on the calculations and considering potential volume minimums, the nurse should administer 8 mL of the phenytoin suspension.
Correct Answer is A
Explanation
Choice A rationale:
Candidiasis, also known as thrush, is a fungal infection caused by Candida albicans. It commonly affects the mouth, causing white patches on the tongue, inner cheeks, gums, or tonsils.
Individuals with AIDS often have weakened immune systems due to a decreased CD4 T-cell count. This makes them more susceptible to opportunistic infections like candidiasis.
The fungal infection can spread to the esophagus, causing difficulty swallowing, or even to the bloodstream, leading to more serious complications.
Choice B rationale:
Xerostomia refers to dry mouth. It can be caused by various factors, including medications, salivary gland dysfunction, or radiation therapy. While it can occur in individuals with AIDS, it's not directly linked to a decreased CD4 T-cell count.
Choice C rationale:
Halitosis, or bad breath, can have multiple causes, including poor oral hygiene, gum disease, or digestive issues. It's not specifically associated with AIDS or a decreased CD4 T-cell count.
Choice D rationale:
Gingivitis is inflammation of the gums, often caused by plaque buildup. It's a common condition, but it's not directly linked to AIDS or a decreased CD4 T-cell count.
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