A nurse is caring for a patient with rheumatoid arthritis. The patient is prescribed hydroxychloroquine to slow the progression of the disease. Which of the following laboratory results should the nurse monitor for this patient?
Decreased white blood cell count
Increased blood cell count
Decreased platelet count
Increased red blood cell count
The Correct Answer is A
Choice A rationale:
Hydroxychloroquine can cause a rare but serious side effect called bone marrow suppression. This is a decrease in the production of blood cells in the bone marrow.
White blood cells (WBCs) are a key component of the immune system, and a decrease in WBCs can make a patient more susceptible to infections.
Therefore, it's crucial for nurses to monitor the patient's WBC count to detect any potential bone marrow suppression early and take necessary actions to prevent or manage infections.
Choice B rationale:
An increased blood cell count is not a typical side effect of hydroxychloroquine.
Some conditions, like polycythemia vera, can cause an increase in blood cell count, but they are not related to hydroxychloroquine use.
Choice C rationale:
While hydroxychloroquine can sometimes cause a decrease in platelet count, it's less common than bone marrow suppression affecting WBCs.
However, it's still essential for nurses to monitor platelet counts as well, as a significantly low platelet count can impair blood clotting and increase the risk of bleeding.
Choice D rationale:
Hydroxychloroquine does not typically affect red blood cell (RBC) counts.
Conditions that affect RBC counts, such as anemia, are not directly related to hydroxychloroquine use.
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Related Questions
Correct Answer is A
Explanation
Choice A rationale:
Pain management: Rheumatoid arthritis (RA) is a chronic inflammatory disease that causes pain, stiffness, swelling, and fatigue in the joints. Pain is often the most debilitating symptom of RA, and it can significantly impact a person's quality of life.
Therefore, the nurse's primary consideration is to ensure the client's comfort by effectively managing their pain. This may involve using a variety of interventions, such as:
Administering pain medications as prescribed Applying heat or cold therapy
Using assistive devices to reduce joint strain
Teaching the client about pain management techniques, such as relaxation exercises and pacing activities
Promoting rest and sleep: Rest and sleep are essential for healing and reducing inflammation. The nurse can encourage the client to rest during the day and to get enough sleep at night.
Creating a comfortable environment: The nurse can help to create a comfortable environment for the client by adjusting the room temperature, providing soft bedding and pillows, and reducing noise and distractions.
Providing emotional support: RA can be a challenging disease to live with, and it can take a toll on a person's emotional well- being. The nurse can provide emotional support by listening to the client's concerns, offering reassurance, and encouraging them to express their feelings.
Choice B rationale:
Motivation is important: While motivation is important for self-management of RA, it is not the primary consideration for the nurse. The nurse's focus is on providing comfort and addressing the client's immediate needs. Once the client's pain and other symptoms are managed, the nurse can then work with the client to develop a plan for managing their RA long-term. This may include providing education about the disease, teaching self-care strategies, and encouraging the client to participate in activities that promote physical and emotional well-being.
Choice C rationale:
Surgery may be an option: Surgery may be an option for some clients with RA, but it is not the primary consideration for the nurse. Surgery is typically considered only after other treatment options have failed to control the client's symptoms.
Choice D rationale:
Education is important: Education is an important part of managing RA, but it is not the primary consideration for the nurse. The nurse's focus is on providing comfort and addressing the client's immediate needs. Once the client's pain and other symptoms are managed, the nurse can then provide education about the disease and its management.
Correct Answer is A
Explanation
Choice A rationale:
Fever is the most reliable early indicator of infection in a client with low WBC because it is a direct physiologic response to the presence of pathogens. When the body detects an infection, it releases pyrogens, which act on the hypothalamus to raise the body's temperature. This elevated temperature helps to create an environment that is less hospitable to bacteria and viruses, and it also stimulates the immune system to fight the infection.
In clients with low WBC, the immune system is already compromised, so the fever response may be even more pronounced. It's important to note that even a slight elevation in temperature (as low as 100.4°F or 38°C) can be significant in these clients.

Choice B rationale:
Chills can also be a sign of infection, but they are not as specific as fever. Chills can occur for other reasons, such as exposure to cold or anxiety.
Choice C rationale:
Tachycardia, or increased heart rate, can also be a sign of infection, but it is not as reliable as fever. Tachycardia can occur for other reasons, such as dehydration, pain, or anxiety.
Choice D rationale:
Dyspnea, or shortness of breath, is not a typical early sign of infection. It is more likely to occur in later stages of infection, when the infection has spread to the lungs.
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