A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil. The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?
Cefuroxime
Metformin
Isosorbide
Naproxen
The Correct Answer is C
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
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Related Questions
Correct Answer is D
Explanation
A. Rh incompatibility primarily affects erythrocytes, resulting in hemolysis rather than clotting abnormalities. Therefore, transient clotting difficulties are not typically associated with this condition.
B. Rh incompatibility doesn't directly cause hypothermia in newborns. The condition primarily leads to hemolytic disease of the newborn, which can result in jaundice, anemia, and other complications, but not hypothermia.
C. Rh incompatibility leads to an increase in bilirubin levels, causing hyperbilirubinemia rather than hypobilirubinemia. This increase in bilirubin levels can lead to jaundice and potentially severe neurological complications in the newborn.
D. This is a severe complication of Rh incompatibility where the fetus experiences severe edema due to hemolytic anemia and heart failure. It results from the destruction of fetal red blood cells by maternal antibodies against Rh-positive blood cells.
Correct Answer is C
Explanation
A. Regular dental check-ups are important for clients taking phenytoin, as it can cause gum hyperplasia.
B. Phenytoin can interact with many medications, so it's essential for the client to inform their healthcare provider before starting any new medications.
C. Phenytoin is typically used as a long-term treatment for seizure disorders. Stopping the medication suddenly can increase the risk of seizures and should only be done under the guidance of a healthcare provider.
D. Phenytoin absorption can be affected by food, so taking it with meals can help reduce gastrointestinal side effects. However, it's important for the client to maintain consistent dosing and timing with or without meals.
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