A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil. The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?
Cefuroxime
Metformin
Isosorbide
Naproxen
The Correct Answer is C
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Clozapine is an antipsychotic medication commonly used to treat schizophrenia.
Reduction in auditory hallucinations is a positive therapeutic outcome indicating the medication's efficacy in managing psychotic symptoms.
B. While clozapine may have antiepileptic properties, it's primarily used for its antipsychotic effects rather than controlling seizures.
C. Weight gain is a common side effect of clozapine rather than an indicator of therapeutic effect.
D. Clozapine is associated with the potential for agranulocytosis, a severe adverse effect characterized by a decreased white blood cell count, but this is not a measure of therapeutic effect.
Correct Answer is A
Explanation
A. Azithromycin is an antibiotic commonly used to treat infections such as chlamydia. While it's generally well-tolerated, it can rarely cause serious side effects such as allergic reactions or severe skin reactions. Sore throat or fever may indicate such adverse effects, and patients
should be instructed to contact their healthcare provider immediately if they experience these symptoms.
B. Dark yellow or orange urine is not a typical side effect of azithromycin. It can be caused by drugs such as rifampin.
C. Taking azithromycin with an antacid is generally not necessary and may interfere with the absorption of the medication. It's usually recommended to take azithromycin on an empty stomach, at least 1 hour before or 2 hours after meals, unless otherwise directed by a healthcare provider.
D. Bleeding gums are not a common side effect of azithromycin. If a patient experiences unusual bleeding or bruising, they should seek medical attention, but this symptom is not specifically associated with azithromycin use.
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