A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil. The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?
Cefuroxime
Metformin
Isosorbide
Naproxen
The Correct Answer is C
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Akathisia refers to a subjective feeling of restlessness and an objective inability to sit still.
It's characterized by a need to move constantly and is not typically associated with choreiform movements, lip smacking, or spastic facial distortions.
B. Dystonia involves sustained or intermittent muscle contractions leading to abnormal postures or twisting movements. It typically presents with muscle spasms, not choreiform movements or lip smacking.
C. Pseudoparkinsonism refers to a collection of symptoms that resemble Parkinson's disease, such as tremor, bradykinesia, rigidity, and postural instability. It does not typically involve choreiform movements or lip smacking.
D. Tardive dyskinesia is a movement disorder characterized by involuntary, repetitive movements of the face and body, including choreiform movements (rapid, jerky movements), lip smacking, and spastic facial distortions. It often develops after long-term use of antipsychotic medications like chlorpromazine and can persist even after discontinuation of the medication.

Correct Answer is A
Explanation
A. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), can cause changes in weight.
Reporting weight changes to the healthcare provider is important for monitoring and managing potential side effects.
B. Fluoxetine and other antidepressants should not be stopped abruptly without consulting a healthcare provider, even if the client starts feeling better. Abrupt discontinuation can lead to withdrawal symptoms and worsening of depression.
C. Fluoxetine does not typically interact with cheese or tyramine-containing foods. This statement reflects a misunderstanding of the medication's dietary restrictions.
D. Fluoxetine is usually taken once daily in the morning due to its potential to cause insomnia as a side effect. Taking it at bedtime may exacerbate sleep disturbances.
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