A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil. The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?
Cefuroxime
Metformin
Isosorbide
Naproxen
The Correct Answer is C
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
Correct Answer is B
Explanation
A. The deltoid muscle is typically used for intramuscular injections in adults, but it is not the preferred site for newborns due to their small muscle mass.
B. The vastus lateralis muscle, located on the lateral aspect of the thigh, is the preferred site for intramuscular injections in newborns and infants due to its large muscle mass and accessibility.
C. While the ventrogluteal site is commonly used for intramuscular injections in adults, it may not be as easily accessible or preferred in newborns.
D. The dorsogluteal site is not recommended for intramuscular injections in newborns due to the risk of injury to the sciatic nerve and other underlying structures.
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