A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil. The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?
Cefuroxime
Metformin
Isosorbide
Naproxen
The Correct Answer is C
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. It is generally advised to use additional forms of contraception or abstain from sexual activity for the first 7 days of the initial cycle.
B. If a pill is missed, the client should follow the specific instructions provided by the healthcare provider or the information leaflet, which typically involves taking the missed pill as soon as remembered and then continuing with the next dose at the regular time. Missed pills should be taken as soon as remembered, even if it means taking two pills in one day, and additional contraceptive measures may be necessary.
C. Increasing the dosage of an estrogen-progestin combination contraceptive for breakthrough bleeding is not a standard recommendation as this could lead to an increased risk of side effects. Breakthrough bleeding may occur, especially during the first few cycles of use, but it typically resolves on its own without the need for dosage adjustment.
D. There's no specific requirement to take combination contraceptives on an empty stomach. They can be taken with or without food, according to individual preference, but should be taken consistently at the same time each day to maximize effectiveness.
Correct Answer is A
Explanation
A. Azithromycin is an antibiotic commonly used to treat infections such as chlamydia. While it's generally well-tolerated, it can rarely cause serious side effects such as allergic reactions or severe skin reactions. Sore throat or fever may indicate such adverse effects, and patients
should be instructed to contact their healthcare provider immediately if they experience these symptoms.
B. Dark yellow or orange urine is not a typical side effect of azithromycin. It can be caused by drugs such as rifampin.
C. Taking azithromycin with an antacid is generally not necessary and may interfere with the absorption of the medication. It's usually recommended to take azithromycin on an empty stomach, at least 1 hour before or 2 hours after meals, unless otherwise directed by a healthcare provider.
D. Bleeding gums are not a common side effect of azithromycin. If a patient experiences unusual bleeding or bruising, they should seek medical attention, but this symptom is not specifically associated with azithromycin use.
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