A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil. The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?
Cefuroxime
Metformin
Isosorbide
Naproxen
The Correct Answer is C
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Alprazolam, a benzodiazepine, typically doesn't cause hypertension. Its primary mechanism of action involves modulation of GABA receptors in the central nervous system, leading to anxiolytic effects rather than effects on blood pressure regulation.
B. There's no documented association between alprazolam use and hearing loss.
Benzodiazepines like alprazolam primarily affect the central nervous system and do not target auditory structures.
C. Sedation is a common side effect of alprazolam due to its CNS depressant properties.
Patients often experience drowsiness, fatigue, and impaired cognitive function, especially when initiating therapy or when doses are increased.
D. Alprazolam typically doesn't cause bradycardia. While it can have mild effects on heart rate, such as tachycardia, significant bradycardia is not a documented adverse effect.
Correct Answer is C
Explanation
A. Tinnitus, or ringing in the ears, is a common adverse effect of aminoglycosides such as gentamycin which cause ototoxicity, rather than erythromycin which is a macrolide.
B. Constipation with abdominal cramping, is not a commonly reported side effect of erythromycin; this medication is more likely to cause diarrhea rather than constipation.
C. Common adverse effects of oral erythromycin include gastrointestinal symptoms such as abdominal cramping and nausea. Therefore, the statement indicating the client is experiencing a common adverse effect would be having a small amount of yellow emesis which aligns with the reported side effects of nausea and vomiting.
D. Swollen lips are not a common adverse effect of erythromycin. This symptom may indicate an allergic reaction or another issue unrelated to the medication.
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