A nurse is collecting data from a client who takes several daily medications and states that he wants to ask the provider for a prescription for sildenafil. The nurse knows that sildenafil is contraindicated due to an interaction with which of the following client's medications?
Cefuroxime
Metformin
Isosorbide
Naproxen
The Correct Answer is C
A. There's no documented interaction between cefuroxime and sildenafil. Cefuroxime is an antibiotic, and there are no known significant interactions with sildenafil.
B. There's no documented interaction between metformin and sildenafil. Metformin, an antidiabetic medication, does not interact significantly with sildenafil.
C. Both sildenafil and isosorbide are vasodilators, and concomitant use can result in severe hypotension due to additive effects on blood pressure lowering. Therefore, their combination is contraindicated.
D. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), does not have a significant interaction with sildenafil. They can be safely used together in most cases, although caution may be needed in individuals with cardiovascular risk factors.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Gentamycin ointment is typically applied to the affected area and then covered with a sterile dressing to enhance absorption and prevent contamination. Leaving it open to the air may reduce its effectiveness.
B. Gentamycin ointment is not known to cause blurry vision, as it is applied topically to the skin and does not typically affect vision.
C. Gentamycin ointment should only be applied to the specific area of infection as directed by the healthcare provider. Applying it to large areas unnecessarily may increase the risk of adverse effects and antibiotic resistance.
D. Proper cleansing of the affected area before applying gentamycin ointment helps remove debris and bacteria, promoting better medication absorption and effectiveness.
Correct Answer is C
Explanation
A. Alprazolam, a benzodiazepine, typically doesn't cause hypertension. Its primary mechanism of action involves modulation of GABA receptors in the central nervous system, leading to anxiolytic effects rather than effects on blood pressure regulation.
B. There's no documented association between alprazolam use and hearing loss.
Benzodiazepines like alprazolam primarily affect the central nervous system and do not target auditory structures.
C. Sedation is a common side effect of alprazolam due to its CNS depressant properties.
Patients often experience drowsiness, fatigue, and impaired cognitive function, especially when initiating therapy or when doses are increased.
D. Alprazolam typically doesn't cause bradycardia. While it can have mild effects on heart rate, such as tachycardia, significant bradycardia is not a documented adverse effect.
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