A nurse is caring for a client with manifestations of status asthmaticus. Which of the following factors play a role in creating circulatory surge of inflammatory cells and cytokines in this condition? (Select all that apply.)
(Select All that Apply.)
Epithelial cells
OT lymphocytes
Hyperreactivity
Mast cells
Inflammation
Correct Answer : A,D,E
Choice A Reason:
Epithelial cells is correct. Epithelial cells lining the airways play a role in initiating the inflammatory response in asthma by releasing cytokines and other inflammatory mediators. These cells can contribute to the circulatory surge of inflammatory cells and cytokines seen in status asthmaticus.
Choice B Reason:
OT lymphocytes is incorrect. There is no specific cell type known as "OT lymphocytes." It's possible this may refer to T lymphocytes (T cells), which are involved in the immune response in asthma but are not typically associated with a circulatory surge in status asthmaticus.
Choice C Reason:
Hyperreactivity is incorrect. Hyperreactivity refers to the exaggerated response of the airways to various stimuli, leading to bronchoconstriction and inflammation. While hyperreactivity is a characteristic feature of asthma, it does not directly contribute to a circulatory surge of inflammatory cells and cytokines.
Choice D Reason:
Mast cells is correct. Mast cells are key players in the pathophysiology of asthma. They release various inflammatory mediators, including histamine and leukotrienes, which contribute to airway inflammation, bronchoconstriction, and mucus production. Mast cells can participate in the circulatory surge of inflammatory cells and cytokines in status asthmaticus.
Choice E Reason:
Inflammation is correct. Inflammation is a hallmark feature of asthma and plays a central role in the pathogenesis of status asthmaticus. The inflammatory response involves the recruitment and activation of various inflammatory cells, release of cytokines, and other mediators that contribute to airway obstruction and systemic effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A Reason:
"Do panting breaths several times a day." This statement is inappropriate. Panting breaths involve rapid, shallow breathing similar to what a dog does when it's hot. This technique may not be as effective in clearing mucus or promoting lung expansion compared to deep coughing. While panting breaths may have some benefits in promoting ventilation and increasing lung volume, they may not be as targeted or efficient in preventing atelectasis as other techniques such as deep coughing
Choice B Reason:
"Perform deep coughing twice a day." This statement is correct. Deep coughing helps clear mucus and secretions from the airways, reducing the risk of blockages that can lead to atelectasis. It promotes airway clearance and lung expansion, maintaining respiratory function. Regular deep coughing is particularly important for individuals with spinal cord injuries, as they may have impaired cough reflexes or weakened respiratory muscles, increasing their vulnerability to atelectasis.
Choice C Reason:
"Strengthen your chest muscles by performing therapy exercises." This statement is incorrect. While strengthening chest muscles through therapy exercises can be beneficial for overall respiratory health, it may not directly target the prevention of atelectasis. Atelectasis is primarily caused by the collapse of lung tissue due to mucus buildup or reduced lung expansion, rather than weakness of chest muscles. While therapy exercises may have other benefits such as improving respiratory function and endurance, they may not be the most effective strategy for preventing atelectasis in individuals with spinal cord injuries.
Choice D Reason:
"Get plenty of rest throughout the day." This statement is incorrect. Rest is important for overall health and well-being, but it may not directly contribute to the prevention of atelectasis. Inactivity and prolonged bed rest can actually increase the risk of atelectasis by reducing lung expansion and promoting mucus accumulation in the airways. While adequate rest is necessary for recovery and energy conservation, it should be balanced with activities that promote lung expansion and airway clearance, such as deep breathing exercises and mobility.
Correct Answer is D
Explanation
Correct answer: D
Choice A Reason:
Decreased pulmonary vascular resistance is incorrect. Inflammatory mediators released in response to a pulmonary embolism can lead to vasoconstriction and increased pulmonary vascular resistance. This is part of the body's response to redirect blood flow away from the affected area of the lung and maintain adequate perfusion to other areas.
Choice B Reason:
Hypercapnia is incorrect. Hypercapnia refers to elevated levels of carbon dioxide (CO2) in the blood.Hypocapnia usually is present with embolism; hypercapnia, on the other hand, is rare.
Choice C Reason:
Hypoventilation is incorrect. Hypoventilation occurs when there is inadequate ventilation of the lungs relative to metabolic demands. In the context of a pulmonary embolism, hypoventilation can occur due to factors such as pain, respiratory muscle fatigue, or impaired gas exchange, all of which can be influenced by the release of inflammatory mediators.
Choice D Reason:
Respiratory alkalosis is correct.In response to the blockage and the resulting inflammation, the body often increases the respiratory rate as a compensatory mechanism to maintain adequate oxygen levels and remove carbon dioxide.Due to the increased breathing rate, there is excessive exhalation of carbon dioxide, leading to a decrease in the partial pressure of CO2 in the blood. This results in an increase in blood pH, causing respiratory alkalosis.
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