A nurse is caring for a client with manifestations of status asthmaticus. Which of the following factors play a role in creating circulatory surge of inflammatory cells and cytokines in this condition? (Select all that apply.)
(Select All that Apply.)
Epithelial cells
OT lymphocytes
Hyperreactivity
Mast cells
Inflammation
Correct Answer : A,D,E
Choice A Reason:
Epithelial cells is correct. Epithelial cells lining the airways play a role in initiating the inflammatory response in asthma by releasing cytokines and other inflammatory mediators. These cells can contribute to the circulatory surge of inflammatory cells and cytokines seen in status asthmaticus.
Choice B Reason:
OT lymphocytes is incorrect. There is no specific cell type known as "OT lymphocytes." It's possible this may refer to T lymphocytes (T cells), which are involved in the immune response in asthma but are not typically associated with a circulatory surge in status asthmaticus.
Choice C Reason:
Hyperreactivity is incorrect. Hyperreactivity refers to the exaggerated response of the airways to various stimuli, leading to bronchoconstriction and inflammation. While hyperreactivity is a characteristic feature of asthma, it does not directly contribute to a circulatory surge of inflammatory cells and cytokines.
Choice D Reason:
Mast cells is correct. Mast cells are key players in the pathophysiology of asthma. They release various inflammatory mediators, including histamine and leukotrienes, which contribute to airway inflammation, bronchoconstriction, and mucus production. Mast cells can participate in the circulatory surge of inflammatory cells and cytokines in status asthmaticus.
Choice E Reason:
Inflammation is correct. Inflammation is a hallmark feature of asthma and plays a central role in the pathogenesis of status asthmaticus. The inflammatory response involves the recruitment and activation of various inflammatory cells, release of cytokines, and other mediators that contribute to airway obstruction and systemic effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C","D","E"]
Explanation
Choice A Reason:
Paresthesia is appropriate. Paresthesia, or abnormal sensations such as tingling, numbness, or burning, is a common neurological symptom in individuals with multiple sclerosis. It results from damage to the nerves or disruption of nerve signals in the central nervous system.
Choice B Reason:
Nausea and vomiting is inappropriate. While nausea and vomiting can occur in individuals with multiple sclerosis, they are not considered hallmark symptoms of the disease. These symptoms may be associated with other factors such as medications, autonomic dysfunction, or complications such as urinary tract infections.
Choice C Reason:
Dysphagia is appropriate. Dysphagia, or difficulty swallowing, is a common symptom in individuals with multiple sclerosis, particularly as the disease progresses. It can result from damage to the nerves that control swallowing muscles or from impaired coordination of swallowing reflexes.
Choice D Reason:
Spasticity is appropriate. Spasticity, or muscle stiffness and involuntary muscle contractions, is a common symptom in individuals with multiple sclerosis. It occurs due to damage to the nerve fibers that control muscle movement and can lead to difficulty with movement, walking, and muscle control.
Choice E Reason:
Vertigo is appropriate. Vertigo, or the sensation of spinning or dizziness, can occur in individuals with multiple sclerosis, particularly if lesions develop in areas of the brain involved in balance and coordination.
Correct Answer is B
Explanation
Choice A Reason:
"When did you have your last physical?": This question is relevant to assess the client's overall health status and identify any potential comorbidities or health conditions that may be associated with Parkinson's disease. However, it is not as crucial as asking about family history, which directly addresses the client's potential genetic predisposition to Parkinson's disease.
Choice B Reason:
"Do you have any family members with Parkinson's disease?" Parkinson's disease can have both genetic and environmental factors contributing to its development. While the exact cause of Parkinson's disease is not fully understood, having a family history of the condition is a significant risk factor. Individuals with first-degree relatives (parents, siblings, or children) who have Parkinson's disease have an increased risk of developing the condition themselves.
Choice C Reason:
"What kind of work do you do?": This question aims to gather information about the client's occupational history and potential exposure to environmental toxins or factors that may be associated with Parkinson's disease. Certain occupations or exposures to pesticides, herbicides, heavy metals, or other toxins have been linked to an increased risk of Parkinson's disease. While occupational history is important, it is not as directly relevant to assessing the client's risk factors as asking about family history.
Choice D Reason:
"How much coffee do you drink every day?": Research has suggested that caffeine consumption may be associated with a reduced risk of Parkinson's disease or may potentially delay its onset. However, the evidence is not definitive, and the relationship between caffeine intake and Parkinson's disease is still not fully understood. While caffeine consumption may be a relevant factor to explore, especially if the client has a high intake of coffee, it is not as critical as inquiring about family history, which directly addresses genetic predisposition to Parkinson's disease.
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