A nurse is caring for a client with a prescription for celecoxib (Celebrex). The nurse tells the client to report which of the following adverse drug reactions?

Diarrhea

Headache

Nausea

Chest pressure

Answer and Explanation

The Correct Answer is D

A.   Diarrhea is a known side effect of celecoxib but not typically a sign of a serious reaction.
B.   Headache is a mild side effect that may occur with celecoxib use but is not a severe adverse reaction.
C.   Nausea is a common side effect of many medications, including celecoxib, but is not a critical issue unless severe.
D.   Chest pressure could indicate cardiovascular problems, which is a serious adverse effect of celecoxib and other COX-2 inhibitors. Clients should report this immediately, as it may indicate a risk for myocardial infarction or stroke.

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Correct Answer is C

Explanation

A. Morphine is a full agonist on mu receptors and does not act on kappa receptors in the same way.
B. Naloxone is an opioid antagonist that blocks both mu and kappa receptors.
C. Butorphanol is a mixed opioid agonist-antagonist that acts as an agonist on kappa receptors and an antagonist on mu receptors. It is used for pain management and has a lower risk of dependence compared to full opioid agonists.
D. Acetaminophen does not act on opioid receptors and is not classified as an opioid.

Correct Answer is {"dropdown-group-1":"B","dropdown-group-2":"D"}

Explanation

A. Agitation is not a typical complication of morphine sulfate. In fact, morphine and other opioids generally cause sedation rather than agitation. Agitation may occur in rare cases due to discomfort (such as from constipation) or withdrawal symptoms, but it is not a common complication of morphine use.
B. Respiratory depression is a known and serious complication of morphine sulfate and other opioid medications. Opioids can reduce the body's respiratory drive, leading to slower and less effective breathing. This can be life-threatening, especially with higher doses or if combined with other sedative medications.
C. Dilated pupils (mydriasis) are typically not a complication of morphine use. Opioids, including morphine, typically cause constricted pupils (miosis), which is a hallmark sign of opioid use or overdose. Dilated pupils are more commonly associated with stimulant drug use (e.g., cocaine) or certain medical conditions, not opioids like morphine.
D. Bradycardia (slow heart rate) is a known side effect of morphine sulfate and other opioids. Opioids can affect the autonomic nervous system and cause a decrease in heart rate. This is particularly important to monitor for, especially in patients with existing heart conditions or those taking other medications that might also affect heart rate.
E. Diarrhea is generally not a complication of morphine use. Instead, one of the most common side effects of morphine and other opioids is constipation due to their effect on the gastrointestinal system. Opioids slow down the movement of the intestines, which can lead to constipation, but diarrhea is not a typical response.

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A nurse is caring for a client with a prescription for celecoxib (Celebrex). The nurse tells the client to report which of the following adverse drug reactions?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following medication acts as an antagonist on mu receptors and agonists of kappa receptors?

Correct Answer is C

Explanation

Correct Answer is {"dropdown-group-1":"B","dropdown-group-2":"D"}

Explanation

A nurse is educating a client about interactions with acetylsalicylic acid (Aspirin). Which of the following supplements increases the risk of bleeding in clients who are taking NSAIDs? (Select All That Apply.)

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