A nurse is caring for a client with a new diagnosis of hypertension.
Which of the following medications is used to treat hypertension? (Select All That Apply.)

Choice A rationale

Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.

Choice B rationale

Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.

Choice C rationale

COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.

Choice D rationale

Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.

Choice A rationale

Taking one dose immediately and continuing the regular schedule might not provide sufficient contraceptive protection after missing three days.

Choice B rationale

Using an alternative form of contraception for 7 days is appropriate to ensure continued contraceptive protection after missing doses.

Choice C rationale

Taking two doses over the next two days can help catch up, but using an additional form of contraception for 7 days is also recommended to ensure protection.

Choice D rationale

Continuing the medication as prescribed without any additional precautions could result in ineffective contraception due to the missed doses.