A nurse is caring for a client who is taking digoxin to treat heart failure. Which of the following factors predisposes this client to developing digoxin toxicity?
Taking an HMG CoA reductase inhibitor.
Having a 10-year history of COPD.
Taking a high-ceiling diuretic.
Having a prolapsed mitral valve.
The Correct Answer is C
Taking a high-ceiling diuretic predisposes this client to developing digoxin toxicity because it can cause hypokalemia (low blood potassium level), which increases the sensitivity of the heart to digoxin. Digoxin is a medicine that is used to treat heart failure or arrhythmias (abnormal heart rhythms) by increasing cardiac contractility and controlling the heart rate. Digoxin toxicity happens when there is too much digoxin in the body and it becomes harmful, causing symptoms such as nausea, vomiting, headache, confusion, vision disturbance, and irregular heartbeat.
Choice A is wrong because taking an HMG CoA reductase inhibitor (also called a statin) does not increase the risk of digoxin toxicity.
Statins are lipid-lowering medications used to prevent coronary heart disease by blocking an enzyme involved in cholesterol synthesis.
Statins do not affect the blood potassium level or the sensitivity of the heart to digoxin.
Choice B is wrong because having a 10-year history of COPD (chronic obstructive pulmonary disease) does not increase the risk of digoxin toxicity. COPD is a lung condition that causes breathing difficulties and chronic inflammation.
COPD does not affect the blood potassium level or the sensitivity of the heart to digoxin.
Choice D is wrong because having a prolapsed mitral valve does not increase the risk of digoxin toxicity.
A prolapsed mitral valve is a condition where the valve between the left atrium and left ventricle of the heart does not close properly, allowing some blood to leak back into the atrium.
A prolapsed mitral valve does not affect the blood potassium level or the sensitivity of the heart to digoxin.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
The client should stay upright for at least 15 minutes after taking ferrous gluconate to prevent oesophagal irritation. Choice B is wrong because taking an antacid with ferrous gluconate can decrease its absorption and effectiveness.
Choice C is wrong because taking ferrous gluconate with milk can also reduce its absorption and cause gastrointestinal distress.
Choice D is wrong because black stools are a common and harmless side effect of ferrous gluconate and do not indicate a need to notify the provider. Ferrous gluconate is an iron supplement used to treat or prevent iron deficiency anaemia, a condition where the body does not have enough red blood cells to carry oxygen to the tissues.
Iron is an essential component of haemoglobin, the protein that carries oxygen in the blood.
Correct Answer is ["B","D","E"]
Explanation
Older adults are at higher risk of adverse drug reactions due to multiple health problems, polypharmacy, and decreased renal function.
These factors can affect the pharmacokinetics and pharmacodynamics of pain medications and increase the likelihood of drug interactions, overdosage, or toxicity.
Choice A is wrong because the decreased percentage of body fat does not increase the risk of adverse drug reactions in older adults.
In fact, an increased percentage of body fat can alter the distribution and elimination of some drugs.
Choice C is wrong because an increased rate of absorption does not increase the risk of adverse drug reactions in older adults.
In fact, decreased rate of absorption can occur due to reduced gastric motility and blood flow.
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