A nurse is caring for a client who has multiple sclerosis and is being evaluated for progressive multifocal leukoencephalopathy (PML). Which of the following findings should the nurse recognize as manifestations of this condition?
(Select All that Apply.)
Memory loss
Clumsiness
Tardive dyskinesia
Seizures
Vision difficulty
Correct Answer : A,B,D,E
Choice A Reason:
Memory loss is correct. Memory loss can occur in individuals with PML due to damage to the white matter of the brain caused by the JC virus infection. This damage can affect cognitive function, including memory.
Choice B Reason:
Clumsiness is correct. Clumsiness or lack of coordination is a common neurological symptom of PML. It can result from damage to areas of the brain responsible for motor function and coordination.
Choice C Reason:
Tardive dyskinesia is incorrect. Tardive dyskinesia is a movement disorder characterized by involuntary, repetitive movements, often involving the face, lips, tongue, and limbs. While tardive dyskinesia can occur as a side effect of certain medications, it is not typically associated with PML.
Choice D Reason:
Seizures is correct. Seizures can occur in individuals with PML due to the involvement of the brain's white matter by the JC virus infection. Seizures may present as sudden, uncontrolled movements, altered consciousness, or other neurological symptoms.
Choice E Reason:
Vision difficulty is correct. Vision difficulties, including blurred vision, visual field deficits, and other visual disturbances, are common manifestations of PML. Damage to the optic nerves or areas of the brain involved in visual processing can result in vision difficulties.
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Related Questions
Correct Answer is D
Explanation
Choice A Reason:
Depression is incorrect. While depression can contribute to headaches in some individuals, it is more commonly associated with migraine headaches rather than tension-type headaches or cluster headaches. People with depression may experience changes in neurotransmitter levels and alterations in pain perception, which can exacerbate migraines. However, tension-type headaches and cluster headaches are generally less strongly associated with depression as a precipitating factor compared to migraines.
Choice B Reason:
Smoking is incorrect. Smoking can be a trigger for headaches in some individuals, particularly migraines, due to the vasoconstrictive effects of nicotine and other compounds in tobacco smoke. However, smoking is not universally recognized as a common precipitating factor for tension-type headaches or cluster headaches. While individuals with cluster headaches may have higher rates of smoking compared to the general population, it is not a factor commonly shared with tension-type headaches.
Choice C Reason:
Poor posture is incorrect. Poor posture can contribute to muscle tension and cervical spine strain, which may trigger tension-type headaches. However, poor posture is not typically considered a precipitating factor specific to cluster headaches. While tension-type headaches may be exacerbated by poor posture, cluster headaches are characterized by severe, unilateral pain typically centered around the eye or temple, with associated autonomic symptoms such as tearing, nasal congestion, or ptosis.
Choice D Reason:
Stress is correct. Stress is a well-established precipitating factor for both tension-type headaches and cluster headaches. Stress can lead to muscle tension and contraction, which are common triggers for tension-type headaches. Additionally, stress can also contribute to the onset or worsening of cluster headaches, although the exact mechanisms underlying this association are not fully understood. Therefore, stress is a common precipitating factor for both tension-type headaches and cluster headaches.

Correct Answer is ["A","B","C","E"]
Explanation
Choice A Reason:
"It will be necessary to take a stool softener to keep you from becoming constipated." This instruction is correct. Individuals with spinal cord injuries often experience bowel dysfunction, including constipation, due to decreased mobility and impaired bowel function. Stool softeners can help soften the stool and facilitate easier bowel movements, reducing the risk of constipation and associated complications such as fecal impaction.
Choice B Reason:
"Suprapubic catheterization might have to be done if you are unable to catheterize yourself." This instruction is correct. Suprapubic catheterization involves the insertion of a catheter through the abdominal wall directly into the bladder to drain urine. It may be necessary if the client is unable to perform intermittent catheterization independently or if other methods of bladder management are ineffective or contraindicated.
Choice C Reason:
"You will need to learn how to do self-intermittent catheterization to drain your bladder." This instruction is correct. Self-intermittent catheterization involves inserting a catheter into the bladder to drain urine at regular intervals. It is a commonly used method of bladder management for individuals with spinal cord injuries to prevent urinary retention and bladder distention.
Choice D Reason:
"Do not drink fluids excessively as this may cause diarrhea," is not typically included in bowel and bladder management instructions for individuals with spinal cord injuries. Hydration is important for overall health and may help prevent complications such as urinary tract infections, kidney stones, and constipation. Therefore, option D is not appropriate for inclusion in the teaching for a client with a complete spinal cord injury.
Choice E Reason:
"To achieve a bowel movement, daily digital stimulation will need to be done." This instruction is incorrect. Digital stimulation involves gently stimulating the rectum with a lubricated gloved finger to initiate a bowel movement. It can help individuals with spinal cord injuries who have neurogenic bowel dysfunction to stimulate bowel motility and facilitate bowel evacuation.
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