A nurse is caring for a client who has diabetes insipidus and is receiving desmopressin by intermittent IV bolus. Which of the following manifestations should indicate to the nurse a therapeutic response to the medication?
Increase in serum glucose
Decrease in blood pressure
Decrease in urine output
Increase in WBC count
The Correct Answer is C
Choice A Reason:
Increase in serum glucose is incorrect. Desmopressin, which is a synthetic form of vasopressin, primarily affects water reabsorption in the kidneys and doesn't directly impact glucose levels. Therefore, an increase in serum glucose wouldn't be an expected therapeutic response to desmopressin for diabetes insipidus.
Choice B Reason:
Decrease in blood pressure is incorrect. Desmopressin is primarily used for its antidiuretic effect, concentrating urine by increasing water reabsorption in the kidneys. It typically doesn't have a significant impact on blood pressure. Therefore, a decrease in blood pressure wouldn't typically be an anticipated therapeutic response to desmopressin in this context.
Choice C Reason:
Decrease in urine output is correct. Desmopressin is a synthetic form of vasopressin (antidiuretic hormone) used to treat diabetes insipidus, a condition characterized by excessive urination and extreme thirst due to the inability to concentrate urine. The primary goal of desmopressin is to reduce urine output by increasing water reabsorption in the kidneys, thereby decreasing excessive urination. Therefore, a decrease in urine output would indicate a therapeutic response to the medication in this context.
Choice D Reason:
Increase in WBC count is incorrect. Desmopressin's action is centered on affecting kidney function by regulating water reabsorption and does not involve changes in white blood cell count. Consequently, an increase in WBC count wouldn't be an expected therapeutic response to desmopressin for diabetes insipidus.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A Reason:
Tinnitus, a perception of noise or ringing in the ears, is not typically associated with paroxetine use.
Choice B Reason:
Drowsiness or somnolence is a common adverse effect associated with paroxetine and many other selective serotonin reuptake inhibitors (SSRIs). It's crucial for clients to be aware of this potential side effect, especially when starting the medication or adjusting the dosage. It might affect their ability to perform tasks requiring alertness, such as driving or operating machinery.
Choice C Reason:
Peripheral edema, or swelling in the extremities, is not a common adverse effect linked specifically to paroxetine use.
Choice D Reason:
Alopecia is correct. Alopecia, or hair loss, is not a commonly reported adverse effect of paroxetine.
Correct Answer is C
Explanation
Choice A Reason:
Meloxicam is incorrect. Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used primarily for managing mild to moderate pain and inflammation. While it can provide relief for mild pain, it may not be potent enough to effectively manage severe pain, especially in cases of advanced cancer-related pain, where stronger analgesics are often necessary.
Choice B Reason:
Aspirin is incorrect. Aspirin, like meloxicam, is an NSAID used for mild to moderate pain relief and has anti-inflammatory properties. While it can be effective for certain types of pain, it's generally not the first choice for severe pain management, particularly in cases of advanced cancer-related pain where stronger opioids are typically required for adequate relief.
Choice C Reason:
Hydromorphone is correct. Hydromorphone is a potent opioid analgesic used to manage severe pain, especially in cancer-related pain or post-operative settings. In cases of severe pain, opioids like hydromorphone are commonly utilized due to their effectiveness in providing relief.
Choice D Reason:
Caldofor is incorrect. The term "Caldofor" does not appear to correspond to any recognized medication commonly used for pain relief. It's possible that this might be a misspelling or an unfamiliar or less common drug name. Without a specific drug identification, it's challenging to assess its suitability or effectiveness for managing severe pain associated with pancreatic cancer.

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