A nurse is caring for a client who has diabetes insipidus and is receiving desmopressin by intermittent IV bolus. Which of the following manifestations should indicate to the nurse a therapeutic response to the medication?
Increase in serum glucose
Decrease in blood pressure
Decrease in urine output
Increase in WBC count
The Correct Answer is C
Choice A Reason:
Increase in serum glucose is incorrect. Desmopressin, which is a synthetic form of vasopressin, primarily affects water reabsorption in the kidneys and doesn't directly impact glucose levels. Therefore, an increase in serum glucose wouldn't be an expected therapeutic response to desmopressin for diabetes insipidus.
Choice B Reason:
Decrease in blood pressure is incorrect. Desmopressin is primarily used for its antidiuretic effect, concentrating urine by increasing water reabsorption in the kidneys. It typically doesn't have a significant impact on blood pressure. Therefore, a decrease in blood pressure wouldn't typically be an anticipated therapeutic response to desmopressin in this context.
Choice C Reason:
Decrease in urine output is correct. Desmopressin is a synthetic form of vasopressin (antidiuretic hormone) used to treat diabetes insipidus, a condition characterized by excessive urination and extreme thirst due to the inability to concentrate urine. The primary goal of desmopressin is to reduce urine output by increasing water reabsorption in the kidneys, thereby decreasing excessive urination. Therefore, a decrease in urine output would indicate a therapeutic response to the medication in this context.
Choice D Reason:
Increase in WBC count is incorrect. Desmopressin's action is centered on affecting kidney function by regulating water reabsorption and does not involve changes in white blood cell count. Consequently, an increase in WBC count wouldn't be an expected therapeutic response to desmopressin for diabetes insipidus.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A Reason:
"You should report monthly to have your blood drawn to monitor kidney function while taking medication." Is incorrect. While monitoring kidney function might be necessary during tuberculosis treatment due to potential medication side effects, monthly blood draws specifically for kidney function might not be standard. However, periodic blood tests to monitor various parameters, including kidney function, are part of tuberculosis treatment monitoring.
Choice B Reason:
"You will need to take two or more medications to treat your disease." Is correct. Treatment for active pulmonary tuberculosis typically involves a combination of antimicrobial medications to effectively treat the infection and prevent antibiotic resistance. This multidrug therapy is essential to combat the bacteria causing tuberculosis and reduce the risk of treatment failure or relapse.
Choice C Reason:
"You will need to undergo tuberculin skin tests every 6 months while taking medication for your disease." Is incorrect. Tuberculin skin tests are used for screening or diagnosing tuberculosis but are not typically repeated every six months during active treatment for the disease.
Choice D Reason:
"You should anticipate taking medication to treat your disease for at least the next 3 years." Is incorrect. The duration of treatment for active pulmonary tuberculosis varies but is typically shorter than three years. Treatment duration usually lasts several months to a year, depending on the specific medication regimen and the response to treatment.

Correct Answer is A
Explanation
Choice A Reason:
The medication vial sat at room temperature for 2 hr before it was administered is correct. Medications like filgrastim typically have specific storage requirements, including temperature control. Allowing the medication vial to sit at room temperature for an extended period may compromise its stability or effectiveness, leading to potential concerns regarding medication safety. Reporting incidents related to improper medication storage is essential to ensure patient safety and prevent similar occurrences in the future.
Choice B Reason:
The client's absolute neutrophil count was 2,500/mm3 before the medication was administered. Is incorrect. A normal or adequate absolute neutrophil count (ANC) of 2,500/mm3 before administering filgrastim is not an adverse event that requires an incident report.
Choice C Reason:
The nurse flushed the client's IV line with dextrose 5% in water before and after the medication was administered. Is incorrect. Flushing the IV line with dextrose 5% in water is a standard practice and not considered an adverse event or reason for filing an incident report.
Choice D Reason:
The client had chemotherapy 12 hr before the medication was administered. Is incorrect. The timing of previous chemotherapy administration, in this case, doesn't inherently suggest an adverse event requiring an incident report.
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