A nurse is caring for a client who has a prescription for epoetin alfa. Which of the following routes should the nurse plan to use for administration?

Intranasal

Oral

Subcutaneous

Transdermal

Answer and Explanation

The Correct Answer is C

A. Epoetin alfa is not administered intranasally.

B.   Epoetin alfa is not administered orally because it would be destroyed by digestive enzymes and have poor absorption.
C.   Epoetin alfa is typically administered subcutaneously, as it is a recombinant human erythropoietin that stimulates red blood cell production.
D.   Epoetin alfa is not administered trans dermally.

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Correct Answer is B

Explanation

A. 0.45% sodium chloride: 0.45% sodium chloride solution, also known as half-normal saline, is a hypotonic solution used for rehydration and maintenance fluid therapy. However, in cases of
major burns where there is a significant loss of fluid and electrolytes, isotonic solutions are generally preferred.
B. Lactated Ringer's: Lactated Ringer's solution is an isotonic crystalloid solution that closely resembles the electrolyte composition of extracellular fluid. It is commonly used for fluid resuscitation in clients with major burns to replace lost fluids and electrolytes and restore
intravascular volume.

C. Dextrose 5% in water: Dextrose 5% in water is a hypotonic solution used primarily for hydration in clients with normal electrolyte levels or as a vehicle for administering medications.
It is not typically used for fluid resuscitation in clients with major burns, as it does not adequately replace lost electrolytes.
D. Dextrose 5% in 0.45% sodium chloride: This solution combines dextrose 5% and 0.45% sodium chloride and is used for maintenance fluid therapy and mild dehydration. However, in cases of major burns where there is significant fluid and electrolyte loss, isotonic solutions like lactated Ringer's or normal saline are preferred for fluid resuscitation.

A. Insomnia B. Fluid retention C. Tinnitus D. Orthostatic hypotension

Correct Answer is B

Explanation

A. Insomnia: Pioglitazone is not typically associated with insomnia as an adverse effect.

Insomnia is more commonly associated with stimulant medications or certain medical conditions.
B. Fluid retention: Pioglitazone, a thiazolidinedione, can cause fluid retention as an adverse effect. This can lead to peripheral edema and exacerbation of heart failure, particularly in

susceptible individuals. Monitoring for signs and symptoms of fluid retention, such as peripheral edema and weight gain, is essential.
C. Tinnitus: Tinnitus is not a commonly reported adverse effect of pioglitazone. Tinnitus is more commonly associated with medications such as certain antibiotics, NSAIDs, and ototoxic drugs.
D. Orthostatic hypotension: Orthostatic hypotension is not typically associated with pioglitazone.

It is more commonly associated with medications that affect blood pressure regulation, such as antihypertensives and alpha-blockers.

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A nurse is caring for a client who has a prescription for epoetin alfa. Which of the following routes should the nurse plan to use for administration?

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Naxlex Comprehensive Predictor Exams

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Correct Answer is B

Explanation

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Correct Answer is B

Explanation

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