A nurse is caring for a child who has recurrent otitis media. The child weighs 14.9 kg (33 lb). A prescription is written for amoxicillin 40 mg/kg PO to be given in two divided doses per day. The pharmacy provides the nurse with amoxicillin 250 mg/5 mL. How many mL of the medication should the nurse plan to administer for each dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

A. "My appetite is increased." Diphenhydramine is an antihistamine that primarily treats allergic reactions by blocking histamine receptors. While antihistamines can sometimes cause increased appetite as a side effect, this is not an indicator of effectiveness in treating an allergic reaction.

B. "I don't have a headache anymore." While diphenhydramine may help with headaches due to its sedative and antihistamine effects, headache relief is not the primary goal when treating an allergic reaction. The effectiveness of diphenhydramine in this scenario should be assessed based on improvements in allergic symptoms rather than headache relief.

C. "My voice is no longer hoarse." Hoarseness can be a sign of airway involvement due to allergic reaction-related swelling (laryngeal edema). Diphenhydramine reduces histamine-induced inflammation, which can help resolve airway symptoms. Improvement in hoarseness suggests reduced swelling and a lower risk of airway obstruction, making this the best indicator of effectiveness.

D. "I am feeling more alert." Diphenhydramine commonly causes drowsiness due to its sedative effects. Feeling more alert would be an unusual response to the medication and does not indicate improvement in the allergic reaction. The primary concern is symptom resolution, particularly respiratory symptoms, rather than changes in alertness.

A. Orthostatic hypotension. Prednisone does not typically cause orthostatic hypotension. Instead, corticosteroids can lead to fluid retention and hypertension due to their effects on sodium and water balance. Orthostatic hypotension is more commonly associated with medications such as diuretics or antihypertensives.

B. Hyperglycemia. Prednisone is a glucocorticoid that increases blood glucose levels by enhancing gluconeogenesis and reducing insulin sensitivity. This effect can make blood sugar more difficult to control in clients who take insulin, potentially requiring higher insulin doses to maintain glycemic control. Clients with diabetes or those taking insulin should closely monitor their blood glucose levels while on prednisone.

C. Paresthesia. Paresthesia (numbness or tingling) is not a common adverse effect of prednisone or a direct interaction with insulin. While uncontrolled diabetes can cause diabetic neuropathy, prednisone does not typically cause neurological symptoms like tingling.

D. Jaundice. Prednisone is not commonly associated with hepatotoxicity or liver dysfunction leading to jaundice. However, long-term corticosteroid use may increase liver enzyme levels, but it does not typically cause direct liver damage or bile obstruction. Jaundice would require evaluation for other underlying liver conditions.