A nurse is caring for a child who has a penicillin allergy.
Which of the following prescriptions should the nurse verify with the provider?

Erythromycin

Amphotericin B

Amoxicillin-clavulanate

Gentamicin

Choice D rationale:

Answer and Explanation

The Correct Answer is C

Choice A rationale:

Erythromycin Erythromycin is a macrolide antibiotic that is often used as an alternative to penicillin. It is generally safe for use in patients with a penicillin allergy. It works by inhibiting bacterial protein synthesis and is effective against a wide range of bacteria.

Choice B rationale:

Amphotericin B Amphotericin B is an antifungal medication, not an antibiotic. It is used to treat serious, systemic fungal infections. It has no cross-reactivity with penicillin, so it would not be a concern for a patient with a penicillin allergy.

Choice C rationale:

Amoxicillin-clavulanate Amoxicillin-clavulanate is a type of penicillin antibiotic. Patients with a known penicillin allergy should avoid this medication, as they may have a cross-reactivity to it. This is why the nurse should verify this prescription with the provider.

Choice D rationale:

Gentamicin Gentamicin is an aminoglycoside antibiotic used to treat serious bacterial infections caused by gram-negative bacteria. It is not related to penicillin and would be safe for a patient with a penicillin allergy.

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Correct Answer is C

Explanation

Choice A rationale:

Proton pump inhibitors (PPIs) are used extensively for the treatment of gastric acid-related disorders, often over the long term, which raises the potential for clinically significant drug interactions in patients receiving concomitant medications.

However, there is no specific mention of a significant interaction between PPIs and aminoglycosides.

Choice B rationale:

Aminoglycoside antibiotics and calcium channel blockers can interact at the neuromuscular junctions. This interaction is of clinical significance because when these agents are given concurrently during the perioperative period they may lead to respiratory depression or prolonged apnea. However, this is not directly related to the therapeutic effect of aminoglycosides, but rather a side effect of their combined use.

Choice C rationale:

The loop-diuretics (ethacrynic acid, furosemide, bumetamide) and aminoglycoside antibiotics (kanamycin, gentamicin, tobramycin, amikacin, etc.) are important drugs frequently used to treat seriously ill patients. Not uncommonly both types of drugs are given to the same patient exposing that patient to the risk of a hearing loss (ototoxicity)5. In addition, the risk of ototoxicity could be enhanced by the concomitant use of loop diuretics and aminoglycoside antibiotics.

Choice D rationale:

Phenytoin is a medication used to treat seizures. It has a complex pharmacokinetic profile and can interact with many other drugs. However, there is no specific mention of a significant interaction between phenytoin and aminoglycosides.

Correct Answer is ["2"]

Explanation

Let’s solve the medication math problem step by step:

Step 1: Identify the total daily dose of amoxicillin. The total daily dose is 2 gm/day.

Step 2: Convert the total daily dose from grams to milligrams, as the available medication is in milligrams. We know that 1 gm = 1000 mg, so 2 gm = 2000 mg.

Step 3: The total daily dose is divided into two doses. So, each dose will be 2000 mg ÷ 2 = 1000 mg.

Step 4: Determine the number of tablets for each dose. Each tablet contains 500 mg of amoxicillin. So, the number of tablets for each dose is 1000 mg ÷ 500 mg/tablet = 2 tablets.

So, the nurse should administer 2 tablets of amoxicillin with each dose.

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A nurse is caring for a child who has a penicillin allergy. Which of the following prescriptions should the nurse verify with the provider?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is reviewing the medication orders for a patient who will be receiving aminoglycoside therapy. Which other medication or medication class, if ordered, would be a potential interaction concern?

Correct Answer is C

Explanation

A nurse is preparing to administer amoxicillin 2 gm/day PO divided into two doses. The amount available is amoxicillin 500 mg tablets. How many tablets should the nurse administer with each dose?

Correct Answer is ["2"]

Explanation

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A nurse is caring for a child who has a penicillin allergy.
Which of the following prescriptions should the nurse verify with the provider?