A 79-year-old patient is receiving a quinolone for treatment of a complicated incision infection.
For which adverse effect associated with these drugs should the nurse monitor?

Double vision

Tendonitis and tendon rupture

Neuralgia

Hypotension

Answer and Explanation

The Correct Answer is B

Choice A rationale:

Double vision is not a common side effect of quinolones. Quinolones are a type of antibiotic that are used to kill or inhibit the growth of bacteria. While they can have side effects, double vision is not typically one of them.

Choice B rationale:

Tendonitis and tendon rupture are known adverse effects of quinolones. These antibiotics can very rarely cause long-lasting, disabling, and potentially irreversible side effects, sometimes affecting multiple systems, organ classes, and senses. One of these side effects is damage to the tendons, which can manifest as tendonitis (inflammation of the tendon) or even tendon rupture. This is particularly a concern for people older than 60 years and for those with renal impairment or solid-organ transplants because they are at a higher risk of tendon injury.

Choice C rationale:

Neuralgia, or nerve pain, is not a common side effect of quinolones. While these antibiotics can affect the nervous system and cause side effects such as peripheral neuropathy and central nervous system effects, neuralgia is not typically reported.

Choice D rationale:

Hypotension, or low blood pressure, is not typically associated with the use of quinolones. These antibiotics can have various side effects, but a significant drop in blood pressure is not commonly reported.

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Correct Answer is A

Explanation

Choice A rationale:

Zidovudine, also known as AZT, is a medication used for the treatment of human immunodeficiency virus (HIV) infection. One of the major dose-limiting toxic effects of Zidovudine is hematologic toxicity, which manifests clinically as anemia, neutropenia, and sometimes as platelet deficits with onset after several weeks of treatment. This hematologic toxicity is essentially a form of bone marrow suppression. Therefore, bone marrow suppression is the dose-limiting adverse effect of zidovudine therapy.

Choice B rationale:

Retinitis is not a known dose-limiting adverse effect of zidovudine. While zidovudine has a range of side effects, retinitis is not commonly associated with its use.

Choice C rationale:

Renal toxicity is not a known dose-limiting adverse effect of zidovudine. While zidovudine can have various side effects, renal toxicity is not typically one of them.

Choice D rationale:

Hepatotoxicity is not the dose-limiting adverse effect of zidovudine. While severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of zidovudine, it is not considered the dose-limiting adverse effect. The dose-limiting adverse effect is more specifically related to hematologic toxicity, which includes bone marrow suppression.

A. Fluconazole B. Tobramycin C. Ciprofloxacin D. Vancomycin

Correct Answer is C

Explanation

Choice A rationale:

Fluconazole Fluconazole is an antifungal medication used to treat and prevent fungal infections. It works by stopping the growth of certain types of fungus. However, it is not effective against bacterial infections such as anthrax.

Choice B rationale:

Tobramycin Tobramycin is an aminoglycoside antibiotic used to treat various types of bacterial infections, particularly Gramnegative infections. It works by stopping the growth of bacteria. However, it is not typically used to treat anthrax.

Choice C rationale:

Ciprofloxacin Ciprofloxacin is a fluoroquinolone antibiotic used for the treatment of a number of bacterial infections. This includes bone and joint infections, intra-abdominal infections, certain type of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. For the treatment of anthrax, ciprofloxacin is one of the antibiotics that could be used. It works by killing the anthrax or by stopping the anthrax from growing. When the anthrax can’t grow anymore, it dies.

Choice D rationale:

Vancomycin Vancomycin is an antibiotic used to treat a number of bacterial infections. It is recommended intravenously as a treatment for complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus. However, it is not typically used to treat anthrax.

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A 79-year-old patient is receiving a quinolone for treatment of a complicated incision infection. For which adverse effect associated with these drugs should the nurse monitor?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A patient who is HIV-positive has been receiving medication therapy that includes zidovudine. The prescriber has decided to stop the zidovudine due to its dose-limiting adverse effect. Which of these conditions is the dose-limiting adverse effect of zidovudine therapy?

Correct Answer is A

Explanation

A nurse is caring for a client who was exposed to anthrax. Which of the following antibiotics should the nurse plan to administer?

Correct Answer is C

Explanation

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A 79-year-old patient is receiving a quinolone for treatment of a complicated incision infection.
For which adverse effect associated with these drugs should the nurse monitor?