A nurse is preparing to administer amoxicillin 2 gm/day PO divided into two doses.

The amount available is amoxicillin 500 mg tablets.

How many tablets should the nurse administer with each dose?

Choice A rationale:

Rifampin is an antibiotic used to treat or prevent tuberculosis (TB). However, the treatment with this medication typically lasts longer than one month. In fact, TB treatment usually involves taking several drugs for a long time.

Choice B rationale:

While it’s important to take some medications with meals to increase absorption or decrease stomach upset, rifampin should be taken at least 1 hour before or 2 hours after a meal. This helps to ensure optimal absorption of the medication.

Choice C rationale:

Insomnia is not typically listed as a common side effect of rifampin. The medication can cause a number of side effects, but these more commonly include things like upset stomach, loss of appetite, nausea, vomiting, diarrhea, and changes in behavior.

Choice D rationale:

One of the known side effects of rifampin is that it can cause a red-orange discoloration of body fluids, including urine, sweat, saliva, and tears. This can be alarming to patients if they are not forewarned, so it’s important for the nurse to provide this information during discharge instructions.

Choice A rationale:

This choice is incorrect. While it’s true that antiviral drugs can be effective in treating the flu, they’re most effective when started within 48 hours of symptom onset. Starting treatment after 4 days may not provide the same benefits.

Choice B rationale:

This choice is incorrect. While a blood test can confirm the presence of the flu virus, it’s not typically necessary to diagnose the flu. Diagnosis is usually based on symptoms and the fact that the flu is widespread in the community.

Choice C rationale:

This choice is correct. Antiviral drugs are most effective when started within 2 days of symptom onset. After this time, the benefits of these drugs decrease. Therefore, starting treatment 4 days after symptoms begin may not significantly reduce the duration or severity of symptoms.

Choice D rationale:

This choice is incorrect. While it’s true that getting a flu vaccine is important, it’s not the best response in this situation. The flu vaccine won’t treat current illness. It’s designed to prevent future infections. In this case, the individual is already sick, so a booster vaccination wouldn’t be the most effective course of action.