A nurse is aware that an accidental administration of a dose greater than recommended is most likely to result in what negative consequence?
Decreased side effects
Lowered therapeutic threshold
Toxicity
Decreased effectiveness
The Correct Answer is C
An accidental administration of a dose greater than recommended can result in toxicity. This means that the medication reaches harmful levels in the body and can cause damage to organs or other adverse effects.
Option A is incorrect because an overdose is more likely to increase side effects rather than decrease them.
Option B is incorrect because a lowered therapeutic threshold means that a lower dose of medication is needed to achieve the desired effect, which is not related to an overdose.
Option D is incorrect because an overdose can increase the effectiveness of the medication to dangerous levels, rather than decrease it.
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Correct Answer is D
Explanation
Flumazenil is a benzodiazepine antagonist that can be used as an antidote for lorazepam overdose ¹. It works by reversing the effects of benzodiazepines such as lorazepam ¹.
Option A is not correct because naloxone is an opioid antagonist and is not used to treat benzodiazepine overdose.
Option B is not correct because acetylcysteine is used to treat acetaminophen overdose and is not used to treat benzodiazepine overdose.
Option C is not correct because physostigmine is used to treat anticholinergic toxicity and is not used to treat benzodiazepine overdose.
Correct Answer is A
Explanation
The half-life of a medication is the time it takes for the concentration of the medication in the body to decrease by half. In this case, the medication has a half-life of 2 hours and a current toxic level of 40 mEq/dL. After 2 hours, the level will decrease to 20 mEq/dL. After another 2 hours (4 hours total), the level will decrease to 10 mEq/dL, which is within the normal range. However, it will take another 21 half-lives (42 hours) for the level to reach 5 mEq/dL, which is the lower end of the normal range. Therefore, it will take a total of 25 hours (4 + 21) for the medication to reach the normal range.
Option B is incorrect because it would take much longer than 24 hours for the medication to reach the normal range.
Option C is incorrect because it would only take 2 hours for the medication to decrease by half, not reach the normal range.
Option D is incorrect because it would take longer than 4 hours for the medication to reach the normal range.
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