A nurse is assisting with teaching a class about Freud's psychosexual stages. The nurse should reinforce that fixation at the oral stage of development can lead to which of the following conditions?

Choice A reason : Dry mouth, also known as xerostomia, is a common side effect of diphenhydramine, an antihistamine used to treat insomnia among other conditions. It occurs because diphenhydramine has anticholinergic properties, which means it inhibits the action of the neurotransmitter acetylcholine. This inhibition can reduce saliva production, leading to a feeling of dryness in the mouth.

Choice B reason : Hypertension, or high blood pressure, is not a typical side effect of diphenhydramine. While some medications, particularly decongestants, can raise blood pressure, diphenhydramine does not usually have this effect. However, individuals with pre-existing heart conditions should consult a healthcare provider before using it.

Choice C reason : Memory loss is not commonly listed as a side effect of diphenhydramine. However, because it can cause drowsiness and has sedative effects, it may lead to temporary forgetfulness or confusion, especially in older adults or when taken in higher doses.

Choice D reason : 'Medications' is not an adverse reaction but rather a general term for drugs used to diagnose, treat, or prevent illness. In the context of diphenhydramine, it would be more appropriate to discuss specific side effects or adverse reactions related to its use.

Choice A reason : Asthma is a chronic condition characterized by respiratory symptoms such as wheezing, shortness of breath, and coughing due to airway inflammation and constriction. While genetic and environmental factors contribute to the development of asthma, there is no direct correlation between advanced maternal age and an increased risk of asthma in offspring. Asthma's etiology is multifactorial and more closely related to family history, exposure to allergens, and respiratory infections during early childhood.

Choice B reason : Spina bifida is a neural tube defect that occurs when the spine and spinal cord don't form properly. It's associated with factors such as folic acid deficiency during early pregnancy, certain medications, diabetes, and obesity. Although advanced maternal age may slightly increase the risk of chromosomal abnormalities, it is not considered a significant risk factor for spina bifida. Adequate intake of folic acid before conception and during early pregnancy is the most effective prevention strategy.

Choice C reason : Down syndrome is a genetic disorder caused by the presence of an extra copy of chromosome 21 (trisomy 21). The risk of conceiving a child with Down syndrome increases with maternal age, particularly after age 35. This is due to the higher likelihood of nondisjunction events during cell division in older eggs, leading to an abnormal number of chromosomes. Advanced maternal age is a well-established risk factor for Down syndrome, and prenatal screening is recommended to assess the risk.

Choice D reason : Facial malformations, such as cleft lip or palate, are congenital anomalies that can affect the appearance and function of a child's face. These conditions are influenced by genetic and environmental factors, including certain medications, nutritional deficiencies, and exposure to harmful substances during pregnancy. While advanced maternal age may contribute to an increased risk of chromosomal abnormalities, it is not specifically linked to an increased risk of isolated facial malformations.