A nurse is assisting in explaining the pathophysiology of systemic inflammatory response syndrome (SIRS) to a group of newly licensed nurses. Which of the following statements by the nurse is accurate?
"Activation of the inflammatory cascade causes increased perfusion."
The major organ prone to injury during SIRS is the heart."
Spleen dysfunction causes blood clotting issues."
"A deregulated cytokine storm causes an inflammatory response."
The Correct Answer is D
A. Activation of the inflammatory cascade in SIRS typically leads to decreased perfusion and tissue damage due to widespread inflammation and capillary leakage.
B. SIRS can affect multiple organs, but it is particularly known for impacting the lungs and kidneys rather than the heart.
C. While SIRS can involve coagulation issues, these are not specifically due to spleen dysfunction but rather to the widespread inflammatory response.
D. SIRS is driven by a deregulated cytokine storm, which leads to an excessive and uncontrolled inflammatory response, potentially resulting in multiple organ failure.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Restlessness is a sign of hypoxia, indicating that oxygenation might still be inadequate.
B. A heart rate of 110/min suggests tachycardia, which can also be associated with ongoing hypoxia.
C. A respiratory rate of 28/min is elevated and may indicate continued respiratory distress or hypoxia.
D. Pink mucous membranes are a sign of adequate oxygenation and indicate that the supplemental oxygen is effective in resolving the hypoxia.
Correct Answer is A
Explanation
A. Hepatotoxicity is not a primary sign of salicylate toxicity; salicylate toxicity is more commonly associated with gastrointestinal issues, mental confusion, and tinnitus.
B. GI bleeding is a common sign of salicylate toxicity due to its effect on the gastrointestinal lining.
C. Mental confusion can occur as a result of salicylate toxicity affecting the central nervous system.
D. Tinnitus is a classic symptom of salicylate toxicity.
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