A nurse is assessing a client who is receiving a dose of IV amphotericin B. Which of the following findings should indicate to the nurse that the client is experiencing an acute infusion reaction?

A. Advise the client to change positions slowly: The client's symptoms of dizziness and light- headedness upon standing suggest orthostatic hypotension, which can be managed by advising the client to change positions slowly to minimize blood pressure drops upon standing.
B. Check the client for orthostatic hypotension. Monitor the client for dysrhythmias: The client's symptoms, along with the report of waking up at night to void, are suggestive of orthostatic hypotension, a drop in blood pressure upon standing. Checking for orthostatic hypotension and monitoring for dysrhythmias are appropriate nursing actions to assess and manage this condition.

C. Advise the client to restrict potassium intake: Restricting potassium intake is not indicated based on the client's symptoms of dizziness and light-headedness. This action is not relevant to the situation described.
D. Advise the client to take the medication before bedtime: There is no indication in the scenario provided that medication timing is related to the client's symptoms. This action is not relevant to addressing the client's reported symptoms.

A. Hang the TPN solution to gravity to infuse: TPN solutions are typically administered using an infusion pump to control the rate of infusion accurately. Hanging the solution to gravity is not recommended because it may lead to inconsistent flow rates and inaccurate delivery of nutrients.
B. Titrate TPN solution to blood pressure: TPN solutions are not titrated based on blood pressure.

The composition and rate of TPN infusion are typically determined by the client's nutritional needs and metabolic status, not blood pressure.

C. Monitor the client's weight daily: Monitoring the client's weight daily is essential when administering TPN to assess for fluid balance, nutritional status, and response to therapy. Changes in weight can indicate fluid retention, dehydration, or changes in nutritional status, which may require adjustments to the TPN regimen.
D. Obtain the client's blood glucose level weekly: Blood glucose levels should be monitored frequently in clients receiving TPN, as hyperglycemia is a common complication. Weekly monitoring may not be sufficient to detect and manage hyperglycemia promptly. Therefore,
blood glucose levels are typically monitored more frequently, such as multiple times daily or according to institutional protocols.