A nurse is assessing a client after administering IV vancomycin. Which of the following findings is the nurse's priority to report to the provider?

Choice A reason: Suppressing respiratory effort is the correct purpose of pancuronium. Pancuronium is a neuromuscular blocking agent that paralyzes the skeletal muscles, including the respiratory muscles. This prevents the client from breathing spontaneously and allows the mechanical ventilator to control the ventilation. Pancuronium is used to improve oxygenation and prevent barotrauma in clients with ARDS, who have severe hypoxemia and stiff lungs.

Choice B reason: Decreasing chest wall compliance is not the correct purpose of pancuronium. Chest wall compliance is the measure of how easily the chest wall expands during inspiration. Decreasing chest wall compliance means increasing the resistance to lung expansion, which can worsen the ventilation and oxygenation in clients with ARDS. Pancuronium does not affect the chest wall compliance, but rather the muscle tone.

Choice C reason: Decreasing respiratory secretions is not the correct purpose of pancuronium. Respiratory secretions are the mucus and fluid that are produced by the respiratory tract to moisten and protect the airways. Decreasing respiratory secretions can cause dryness and irritation of the mucous membranes, which can increase the risk of infection and inflammation. Pancuronium does not affect the respiratory secretions, but rather the nerve impulses.

Choice D reason: Inducing sedation is not the correct purpose of pancuronium. Sedation is a state of reduced consciousness, awareness, or responsiveness. Inducing sedation can help to reduce anxiety, pain, and agitation in clients who are mechanically ventilated. Pancuronium does not induce sedation, but rather paralysis. Pancuronium does not affect the central nervous system, but rather the peripheral nervous system. The nurse should administer a sedative agent, such as propofol or midazolam, along with pancuronium to ensure the client's comfort and safety.

Choice A reason: Client report of a headache is not the nurse's priority to report to the provider. A headache is a common and mild side effect of vancomycin, which is an antibiotic used to treat serious infections. A headache may be caused by dehydration, stress, or other factors, and can be relieved by drinking fluids, resting, or taking analgesics.

Choice B reason: Audible inspiratory stridor is the nurse's priority to report to the provider. Stridor is a high-pitched, wheezing sound that occurs when breathing in, and indicates a narrowing or obstruction of the airway. Stridor may be a sign of a severe allergic reaction, or anaphylaxis, to vancomycin, which can be life-threatening. Anaphylaxis can also cause swelling of the face, lips, tongue, or throat, difficulty breathing, low blood pressure, and shock. The nurse should stop the infusion, administer epinephrine, and monitor the client's vital signs.

Choice C reason: Client report of tinnitus is not the nurse's priority to report to the provider. Tinnitus is a ringing or buzzing sound in the ears, and may be a rare and serious side effect of vancomycin. Tinnitus may indicate damage to the inner ear, or ototoxicity, which can lead to hearing loss. The nurse should check the client's hearing and report any changes to the provider. The provider may adjust the dose or frequency of vancomycin, or switch to another antibiotic.

Choice D reason: Localized redness at the catheter insertion site is not the nurse's priority to report to the provider. Redness at the catheter insertion site may indicate irritation, inflammation, or infection of the skin or vein, and may be caused by the needle, the catheter, or the medication. The nurse should inspect the site, clean it with antiseptic, and apply a sterile dressing. The nurse should also monitor the site for signs of phlebitis, such as pain, swelling, warmth, or pus. The nurse may need to change the catheter or the infusion site if the redness persists or worsens.