A nurse in a provider's clinic is caring for a client who reports erectile dysfunction and requests a prescription for sildenafil. Which of the following medications currently prescribed for the client is a contraindication to taking sildenafil?
Metronidazole
Phenytoin
Isosorbide
Prednisone
The Correct Answer is C
Isosorbide is a nitrate vasodilator used to dilate coronary vessels to relieve angina. Sildenafil also dilates peripheral vessels reducing peripheral vascular resistance. Using the two drugs together may lead to lethal drop in blood pressure and shock.
A, B, and D are not contraindicated with Sildenafil as they do not have any significant drug interactions
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Rationale-Warfarin is a coumarin oral anticoagulant. Unlike heparin, warfarin has an onset of action of 4-5 days and requires this duration to give its effect. Before its action takes effect, heparin is required to bridge the gap to prevent clot formation hence the overlap period. IV heparin has no effect on the action of warfarin as an anticoagulant as they have different modes of action
Correct Answer is B
Explanation
Theophylline has a narrow therapeutic window which increase the risk of overdose and toxicity. It is also given at very small doses which could be difficult for the nursing staff to accurately titrate the drops and hence requires an infusion pump
A. Infusion of theophylline loading dose should not exceed 25mg/min due to risk of seizures and cardiac arrhythmias
C. Use of a test dose is not necessary as the risk of hypersensitivity with theophylline is very low.
D. Covering the IV container with dark paper is not necessary for the administration of theophylline.
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