A group of nursing students is reviewing information about upper gastrointestinal system drugs.
The students demonstrate understanding of the material when they identify which of the following as a proton pump inhibitor?

Nizatidine.

Omeprazole.

Sucralfate.

Misoprostol.

Answer and Explanation

The Correct Answer is B

Choice A rationale:

Nizatidine is not a proton pump inhibitor; it is an H2 receptor antagonist. It works by blocking the histamine H2 receptors in the stomach, reducing acid production. Proton pump inhibitors (PPIs) work differently by directly inhibiting the proton pump (H+/K+ ATPase) responsible for acid secretion in the stomach.

Choice B rationale:

Omeprazole is a proton pump inhibitor (PPI). PPIs are drugs that reduce gastric acid production by inhibiting the proton pump (H+/K+ ATPase) in the parietal cells of the stomach. This action is highly effective in treating conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers.

Choice C rationale:

Sucralfate is not a proton pump inhibitor; it is a medication that forms a protective barrier over ulcers and erosions in the stomach and intestines. It does not directly affect acid production.

Choice D rationale:

Misoprostol is not a proton pump inhibitor; it is a synthetic prostaglandin E1 analog. It is primarily used to prevent gastric ulcers in individuals who are at high risk due to chronic nonsteroidal anti-inflammatory drug (NSAID) use. It has a protective effect on the gastric mucosa but does not inhibit acid secretion.

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Correct Answer is C

Explanation

A. Lymphoma. B. Angioneurotic edema. C. Acute renal failure. D. Reye's syndrome.

Correct Answer is D

Explanation

Choice A rationale:

Lymphoma is not a known adverse effect of aspirin use. Reye's syndrome, a rare but severe condition, is associated with aspirin use in children recovering from viral infections such as chickenpox or influenza. Therefore, it is important to be alert to the development of Reye's syndrome when aspirin is administered to a child with these infections.

Choice B rationale:

Angioneurotic edema is not a typical adverse effect of aspirin use in children with chickenpox. Reye's syndrome is the more relevant concern.

Choice C rationale:

Acute renal failure is not a direct result of aspirin use for fever in children. The primary concern in this context is Reye's syndrome, which affects the brain and liver.

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A group of nursing students is reviewing information about upper gastrointestinal system drugs.The students demonstrate understanding of the material when they identify which of the following as a proton pump inhibitor?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following should be included in the nurse's preadministration assessment before administering the first dose of an antineoplastic drug?

Correct Answer is C

Explanation

The parents of a child who is recovering from chickenpox tell the nurse that they gave the child aspirin for his fever.The nurse would be alert to the development of which of the following?

Correct Answer is D

Explanation

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A group of nursing students is reviewing information about upper gastrointestinal system drugs.
The students demonstrate understanding of the material when they identify which of the following as a proton pump inhibitor?