A client with peptic ulcer disease receives a new prescription for cimetidine. Which statement provided by the client requires additional instruction by the nurse?

Choice A reason: A yellow skin color may indicate jaundice, which is a sign of liver damage. Acetaminophen can cause liver toxicity, especially in high doses or with chronic use. The nurse should report this finding to the healthcare provider as soon as possible, as it may require further evaluation and treatment.

Choice B reason: Checking the client's capillary glucose level is not relevant to the finding of yellow skin color. Although diabetes can cause skin changes, such as dryness or infections, it does not cause jaundice. The nurse should focus on the potential liver problem rather than the blood sugar level.

Choice C reason: Using a pulse oximeter to assess oxygen saturation is not helpful in this situation. A low oxygen saturation may indicate hypoxia, which can affect various organs, but it does not cause jaundice. The nurse should monitor the client's respiratory status, but it is not the priority action in response to the yellow skin color.

Choice D reason: Advising the client to reduce the medication dose is not appropriate without consulting the healthcare provider. The client may need acetaminophen for pain relief, and reducing the dose may not be enough to prevent liver damage. The nurse should not make any changes to the medication regimen without the provider's order.

Choice A reason: This is not the most important adverse effect for the nurse to report. Nausea is a common side effect of metoclopramide, which is a prokinetic and antiemetic drug that stimulates the motility of the upper GI tract and blocks the dopamine receptors in the chemoreceptor trigger zone. Nausea may be mild or moderate, and it may subside with time or dose adjustment. The nurse should monitor the client's nausea and provide supportive measures, such as fluids, crackers, or ginger, but it is not a priority.

Choice B reason: This is the most important adverse effect for the nurse to report. Involuntary movements, or extrapyramidal symptoms, are a serious and potentially irreversible side effect of metoclopramide, which can occur due to the blockade of the dopamine receptors in the basal ganglia. Involuntary movements can include dystonia, akathisia, parkinsonism, or tardive dyskinesia, and they can affect the face, neck, limbs, or trunk. The nurse should assess the client for any signs of involuntary movements and notify the healthcare provider immediately. The nurse should also prepare to administer an anticholinergic drug, such as benztropine, to counteract the effects of metoclopramide.

Choice C reason: This is not the most important adverse effect for the nurse to report. Unusual irritability is a rare and mild side effect of metoclopramide, which may be related to the central nervous system effects of the drug. Unusual irritability may manifest as restlessness, anxiety, or agitation, and it may resolve with time or dose adjustment. The nurse should monitor the client's mood and behavior and provide reassurance and comfort, but it is not a priority.

Choice D reason: This is not the most important adverse effect for the nurse to report. Diarrhea is a rare and mild side effect of metoclopramide, which may be related to the increased motility of the GI tract. Diarrhea may be transient or self-limiting, and it may be managed with fluids, electrolytes, or antidiarrheal drugs. The nurse should monitor the client's stool frequency and consistency and provide hydration and hygiene, but it is not a priority.