A client with peptic ulcer disease is experiencing fewer symptoms because of the suppression of hydrochloric acid secretion into the lumen of the stomach.
What category of medication is this client most likely receiving?
Proton pump inhibitor.
Histamine-2 antagonist.
Prostaglandin.
Antipeptic agent.
The Correct Answer is A
This is because proton pump inhibitors (PPIs) are drugs that block the enzyme that produces hydrochloric acid in the stomach, thereby reducing the amount of acid secreted into the lumen. PPIs are commonly used to treat peptic ulcer disease and gastroesophageal reflux disease.
Choice B. Histamine-2 antagonist is wrong because histamine-2 antagonists (H blockers) are drugs that block the action of histamine on the parietal cells of the stomach, thereby reducing the amount of acid secreted into the lumen.
However, PPIs are more potent and effective than H blockers in suppressing acid secretion.
Choice C. Prostaglandin is wrong because prostaglandins are substances that protect the stomach lining from the damaging effects of acid and other factors.
Prostaglandins do not directly affect the secretion of acid into the lumen, but they may increase the production of mucus and bicarbonate that buffer the acid.
Choice D. Antipeptic agent is wrong because antipeptic agents are drugs that form a protective barrier over the ulcer crater, preventing further damage from acid and pepsin.
Antipeptic agents do not affect the secretion of acid into the lumen, but they may enhance healing by creating a favorable environment for tissue repair.
Normal ranges for hydrochloric acid secretion in the stomach are 1.5 to 3.5 liters per day, with a pH of 1.5 to 3.53.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Phenothiazines are contraindicated in patients with suspected or established subcortical brain damage. Phenothiazines are a class of drugs that have antipsychotic, antiemetic, and sedative effects. They act by blocking dopamine receptors in the brain and can cause extrapyramidal symptoms, hypotension, and anticholinergic effects.
Choice B is wrong because phenothiazines are not contraindicated in patients with ischemic heart disease.
However, they can cause orthostatic hypotension and cardiac arrhythmias, so they should be used with caution and monitored closely in these patients.
Choice C is wrong because phenothiazines are not contraindicated in pediatric patients.
However, they can cause sedation, hypotension, and extrapyramidal symptoms, so they should be used with caution and at lower doses in these patients.
Choice D is wrong because phenothiazines are not contraindicated in patients with type 2 diabetes.
However, they can cause hyperglycemia and weight gain, so they should be used with caution and monitored closely in these patients.
Correct Answer is B
Explanation
The client should avoid taking aspirin while taking corticosteroids because of the potential drug-drug interaction between them. This interaction may cause a reduction in the blood levels of aspirin and decrease its effectiveness. It may also increase the risk of gastrointestinal side effects such as inflammation, bleeding, ulceration, and perforation.
Choice A is wrong because dimenhydrinate is an antihistamine that is used to prevent and treat nausea, vomiting, and dizziness.
It does not have a significant interaction with corticosteroids.
Choice C is wrong because ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, inflammation, and fever.
It has a similar interaction with corticosteroids as aspirin, but it is less potent and less likely to cause bleeding.
Choice D is wrong because famotidine is a histamine-2 receptor antagonist that is used to treat and prevent ulcers, gastroesophageal reflux disease (GERD), and other conditions that cause excess stomach acid.
It does not have a significant interaction with corticosteroids.
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