A client on a medical-surgical unit has been diagnosed with Guillain-Barre Syndrome. The nurse understands that in addition to supportive care, which treatment can be used within the first 2 weeks of symptom onset?
Plasmapheresis
Riluzole
Anticholinesterase agents
Acyclovir
The Correct Answer is A
A. Plasmapheresis, also known as plasma exchange, is a treatment where blood plasma containing harmful antibodies is removed from the blood and replaced with donor plasma or albumin. This procedure is effective in reducing the severity and duration of symptoms in GBS by removing the antibodies that attack the peripheral nerves. Plasmapheresis is typically recommended within the first 2 weeks of symptom onset to maximize its benefits.
B. Riluzole is a medication that modulates glutamate neurotransmission and is primarily used in the treatment of amyotrophic lateral sclerosis (ALS). While some studies have explored its potential use in GBS, its efficacy in GBS treatment remains uncertain and it is not considered a standard treatment.
C. Anticholinesterase agents, such as pyridostigmine, are used in conditions characterized by neuromuscular junction dysfunction, such as myasthenia gravis. However, in GBS, where the primary pathology is the demyelination of peripheral nerves rather than neuromuscular junction dysfunction, anticholinesterase agents are not effective and can potentially worsen symptoms.
D. Acyclovir is an antiviral medication primarily used to treat infections caused by herpesviruses, including herpes simplex virus (HSV) and varicella-zoster virus (VZV). It has no role in the treatment of GBS because GBS is not caused by viral infections.
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Related Questions
Correct Answer is C
Explanation
A. Medicare does cover individuals under 65 years old who have end-stage renal disease (ESRD) and meet certain criteria.
B. There are programs that allow individuals with both Medicare and low income to qualify for Medicaid, which can help cover additional healthcare costs that Medicare may not fully cover.
C. While Medicare does provide significant coverage for healthcare services, it is not entirely free of out- of-pocket costs. Medicare Part A typically covers hospital stays, skilled nursing facility care, hospice, and some home health care services with no premiums for most people.
D. Medicare is indeed federally-funded health insurance primarily for individuals aged 65 and older. It also covers certain younger individuals with disabilities and those with ESRD.
Correct Answer is B
Explanation
A. Carbidopa itself does not cross the blood-brain barrier. Its primary role in Sinemet is to inhibit the peripheral breakdown of levodopa (the precursor of dopamine) into dopamine before it reaches the brain.
B. It is true that it may take a few weeks to see the full effects of this medication, as the body needs time to adjust to it.
C. Parkinson's disease is progressive, and as the disease advances, the dosage and frequency of levodopa with carbidopa may need to be adjusted to maintain symptom control. Over time, higher doses or additional medications may be required to manage symptoms effectively.
D. Levodopa does not protect Carbidopa; rather, Carbidopa protects Levodopa from early conversion to dopamine outside the brain, which would make it less effective.
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