A client diagnosed with prostate cancer asks the nurse the importance of the prostate specific antigen (PSA). The nurse explains to the client that the PSA:

is effective in diagnosing other male cancers

is decreased in the presence of cancer

is a screening tool for prostate cancer

is used as a definitive diagnosis for prostate cancer

Answer and Explanation

The Correct Answer is C

A.  PSA is primarily associated with prostate health and is not an effective marker for diagnosing other male cancers. While elevated PSA levels can sometimes indicate issues related to the prostate, they are not used for diagnosing other types of cancer.
B.   In fact, PSA levels are usually increased in the presence of prostate cancer. While there can be some conditions that lead to a decrease in PSA levels, cancer itself typically raises PSA levels.
C.  PSA is commonly used as a screening tool for prostate cancer. Elevated PSA levels may prompt further investigation, including biopsies, to determine if cancer is present. However, it’s important to note that elevated PSA can also occur due to benign conditions like prostatitis or benign prostatic hyperplasia (BPH).
D.  While PSA levels can indicate the possibility of prostate cancer, they do not provide a definitive diagnosis. A diagnosis of prostate cancer typically requires further testing, such as a prostate biopsy, to confirm the presence of cancerous cells.

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Correct Answer is D

Explanation

A. Trisomy 21 is a chromosomal disorder resulting in Down syndrome. While individuals with Down syndrome have an increased risk of developing certain leukemias (such as acute lymphoblastic leukemia), it is not directly associated with CML.
B. Fragile X syndrome is a genetic condition caused by a mutation in the FMR1 gene on the X chromosome, leading to intellectual disability and other developmental issues. It is not associated with CML or any form of leukemia. This option is unrelated to the genetic abnormalities seen in CML.
C. The BRCA1 gene mutation is associated with an increased risk of breast and ovarian cancers. While mutations in BRCA1 can affect cancer susceptibility, they are not linked to Chronic Myelogenous Leukemia. Thus, this option does not apply to CML.
D. The Philadelphia chromosome is a specific genetic abnormality found in the majority of patients with CML. It results from a translocation between chromosomes 9 and 22, creating the BCR-ABL fusion gene, which produces a tyrosine kinase that drives the proliferation of leukemic cells.

A. A career as a corporate attorney who exercises three times per week B. An uncomplicated vaginal birth 12 years ago C. Drinking a glass of red wine with dinner and taking Yoga classes on Saturdays D. Taking birth control pills and a 15-year pack per day smoking habit

Correct Answer is D

Explanation

A. This choice suggests a high-stress job but includes a positive aspect—regular exercise. Regular physical activity is protective against stroke, and being active can help mitigate some risk factors. Therefore, this scenario does not indicate a high risk for stroke.
B. This choice does not present a significant risk factor for stroke. An uncomplicated vaginal birth is typically not associated with an increased risk of stroke. Factors like recent pregnancy could increase risk due to changes in blood coagulation, but 12 years post-birth is not relevant.
C. Moderate alcohol consumption, such as a glass of red wine, may have some cardiovascular benefits when done in moderation, and practicing yoga can be beneficial for stress reduction and overall health. Therefore, this option does not suggest a high risk for stroke.
D. Both smoking and the use of birth control pills significantly increase the risk of stroke, particularly in women. Smoking is a well-known risk factor for cardiovascular disease and can lead to thrombosis (blood clots).

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Blood Cell	Normal Ranges
Red blood cells (mature, circulating)	Male: 451-6.01 million/mm3 Female: 4.01-5.51 million/mm3
Hemoglobin	Adult (15-64 yr) Male 14-17.3 g/dL Female 11.7-155 g/dL
Hematocrit	42%-52% in males 36% -48% in females
Reticulocytes	0.5% -2.5% of total RBC count
White blood cells (total)	4.5-11.1 10/mm3
Neutrophils	59% Bands 3% Segs-56%
Eosinophils	2.7%
Basophils	0.5%
Lymphocytes	34%
Monocytes	4%


Platelets	150,000-450,000/mm3

A client diagnosed with prostate cancer asks the nurse the importance of the prostate specific antigen (PSA). The nurse explains to the client that the PSA:

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Naxlex Comprehensive Predictor Exams

What genetic abnormality would a nurse expect in a client diagnosed with Chronic Myelogenous Leukemia (CML)?

Correct Answer is D

Explanation

The nurse is performing a health screening of a 37-year-old female client. Which factor(s) would alert the nurse that this client is at greatest risk for developing a stroke?

Correct Answer is D

Explanation

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