A child weighing 52.5 pounds receives a prescription for asparaginase 4,780 IU IV. The vial is labeled, "Asparaginase 10,000 IU single-use vial. For IM use, reconstitute in 2 mL sterile sodium chloride, and for IV use, reconstitute in 5 mL". How many mL should the nurse administer?
(Enter the numeric value only. If rounding is required, round to the nearest tenth.)
The Correct Answer is ["2.4"]
Step 1 is to identify the ordered dose and the correct available concentration based on the route of administration.
Ordered Dose: 4,780 IU
Route: IV (Intravenous)
Available Strength: 10,000 IU
Reconstitution Volume for IV: 5 mL
Step 2 is to calculate the volume to administer in milliliters (mL)
Volume = (Ordered Dose ÷ Available Dose) × Available Volume
Volume = (4,780 ÷ 10,000) × 5
4,780 ÷ 10,000 = 0.478
0.478 × 5 = 2.39
Volume to administer = 2.39 mL
Step 3 is to round to the nearest tenth
2.39 rounds to 2.4
Answer: 2.4
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["8"]
Explanation
The total daily dose is 80 mg (20 mg x 4). Since the medication is available in 10 mg tablets, we can calculate the number of tablets required as follows:
80 mg / 10 mg per tablet = 8 tablets
Correct Answer is ["0.75"]
Explanation
The healthcare provider prescribes interferon beta-1b 0.1875 mg every other day for a client with multiple sclerosis.
The nurse reconstitutes the single-use vial of powder labeled 0.3 mg with 1.2 mL of sterile water, so the concentration of interferon beta-1b in the solution is 0.25 mg/mL (0.3 mg / 1.2 mL).
Since the healthcare provider prescribes 0.1875 mg of interferon beta-1b, the nurse should administer 0.75 mL of medication (0.1875 mg / 0.25 mg/mL).

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